EMD-74487

Single-particle
2.86 Å
EMD-74487
3D View Gallery
Deposition: 15/12/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74487

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Raw consensus map of RyR1 in complex with rosuvastatin (Ca2+/CFF/ATP dataset; open pore)

EMD-74487

Single-particle
2.86 Å
EMD-74487
3D View Gallery
Deposition: 15/12/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: Complex of RyR1 with Calstabin-1 in presence of rosuvastatin (Ca2+/CFF/ATP condition)

Deposition Authors: Weninger G, Marks AR
Structural basis for rosuvastatin-induced activation of skeletal muscle ryanodine receptor 1
Weninger G, Reiken S, Yuan Q, Miotto MC, Chang A, Liu Y, Wronska A, Dridi H, Marks AR
(2026) Nat Commun
DOI: doi:10.1038/s41467-026-77372-9
ISSN: 2041-1723