EMD-78784

Single-particle
3.5 Å
EMD-78784
3D View Gallery
Deposition: 24/08/2026
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-78784

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-38fy summary report (pdf.gz) Map-38fy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CYP3A4 bound to vardenafil

EMD-78784

Single-particle
3.5 Å
EMD-78784
3D View Gallery
Deposition: 24/08/2026
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotrimeric complex of CYP3A4
Fitted models: 38fy

Deposition Authors: Orta AK, Fraser JS

Structural analysis of CYP3A4 inhibition by Cryo-EM
Orta AK, Fraser JS
To Be Published
Grant Support: