Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P55085

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
25	unknown peptidase	1-397	P		NT	<%Agarwal et al., 2012[]%>
31	kallikrein-related peptidase 5	26-397	P			Oikonomopoulou et al., 2006
31	kallikrein-related peptidase 14	26-397	P			Oikonomopoulou et al., 2006
34	myeloblastin	26-397	P		MS	Uehara et al., 2002
34	trypsin 1	26-397	N			Loew et al., 2000
34	plasmin	26-397	P			Loew et al., 2000
36	rhodesain	26-397	P		CS	Grab et al., 2009
36	kallikrein-related peptidase 14	26-397	P			Oikonomopoulou et al., 2006
36	peptidase 9 (Dermatophagoides-type)	26-397	P			Sun et al., 2001
36	cationic trypsin (Homo sapiens-type)	26-397	P			Bohm et al., 1996
36	myeloblastin	26-397	P		MS	Uehara et al., 2002
36	tryptase alpha	31-45	P			Molino et al., 1997
36	trypsin 1	26-397	N			Loew et al., 2000
36	thrombin	26-397	P			Loew et al., 2000
36	plasmin	26-397	P			Loew et al., 2000
36	peptidase 3 (Dermatophagoides-type)	26-397	P			Sun et al., 2001
36	kallikrein-related peptidase 6	37-397	P			Oikonomopoulou et al., 2006
36	kallikrein-related peptidase 4	1-397	P		CS	Matsumura et al., 2005
36	matriptase	26-397	P			Uhland, 2006
36	unknown peptidase	26-397	P			Kida et al., 2008
37	pseudolysin	26-397	N			Leduc et al., 2005
38	cathepsin G	26-397	P			Loew et al., 2000
41	kallikrein-related peptidase 14	26-397	P			Oikonomopoulou et al., 2006
41	myeloblastin	26-397	P		MS	Uehara et al., 2002
41	tryptase alpha	31-45	P			Molino et al., 1997
41	trypsin 1	37-397	N			Oikonomopoulou et al., 2006
41	kallikrein-related peptidase 6	37-397	P			Oikonomopoulou et al., 2006
42	elastase-2	26-397	P			Loew et al., 2000
45	calpain-2	26-397	N			Loew et al., 2000
48	elastase-2	26-397	P			Loew et al., 2000
48	myeloblastin	26-397	P			Loew et al., 2000
51	kallikrein-related peptidase 14	26-397	P			Oikonomopoulou et al., 2006
51	trypsin 1	26-397	N			Loew et al., 2000
51	kallikrein-related peptidase 6	37-397	P			Oikonomopoulou et al., 2006
52	pseudolysin	26-397	N			Leduc et al., 2005
53	elastase-2	26-397	P			Loew et al., 2000
55	myeloblastin	26-397	P			Loew et al., 2000
57	myeloblastin	26-397	P			Loew et al., 2000
58	calpain-2	26-397	N			Loew et al., 2000
58	elastase-2	26-397	P			Loew et al., 2000
59	calpain-1	26-397	N			Loew et al., 2000
59	cathepsin G	26-397	P			Loew et al., 2000
61	myeloblastin	26-397	P			Loew et al., 2000
62	myeloblastin	26-397	P			Loew et al., 2000
64	cathepsin G	26-397	P			Loew et al., 2000
71	calpain-2	26-397	N			Loew et al., 2000
72	myeloblastin	26-397	P			Loew et al., 2000
72	trypsin 1	26-397	N			Loew et al., 2000
74	elastase-2	26-397	P			Loew et al., 2000
74	myeloblastin	26-397	P			Loew et al., 2000
75	myeloblastin	26-397	P			Loew et al., 2000
76	elastase-2	26-397	P			Loew et al., 2000
76	myeloblastin	26-397	P			Loew et al., 2000