Substrates for peptidase C01.072: rhodesain

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ala-Leu-Lys-NHMec			Ala-Leu-Lys+NHMec	S		-	Ala	Leu	Lys	AMC	-	-	-	Troeberg et al., 1996
Ala-Phe-Lys-NHMec			Ala-Phe-Lys+NHMec	S		-	Ala	Phe	Lys	AMC	-	-	-	Troeberg et al., 1996
MeOSuc-Asp-Tyr-Met-NHMec			MeOSuc-Asp-Tyr-Met+NHMec	S		MSu	Asp	Tyr	Met	AMC	-	-	-	Troeberg et al., 1996
MeOSuc-Gly-Trp-Met-NHMec			MeOSuc-Gly-Trp-Met+NHMec	S		MSu	Gly	Trp	Met	AMC	-	-	-	Troeberg et al., 1996
Pro-Phe-Arg-NHMec			Pro-Phe-Arg+NHMec	S		-	Pro	Phe	Arg	AMC	-	-	-	Troeberg et al., 1996
proteinase-activated receptor 2	P55085	26-397	peptide-Arg36+Ser-peptide	P	CS	Ser	Lys	Gly	Arg	Ser	Leu	Ile	Gly	Grab et al., 2009
Suc-Ala-Phe-Lys-NHMec			Suc-Ala-Phe-Lys+NHMec	S		Suc	Ala	Phe	Lys	AMC	-	-	-	Troeberg et al., 1996
Suc-Leu-Tyr-NHMec			Suc-Leu-Tyr+NHMec	S		-	Suc	Leu	Tyr	AMC	-	-	-	Troeberg et al., 1996
Val-Leu-Lys-NHMec			Val-Leu-Lys+NHMec	S		-	Val	Leu	Lys	AMC	-	-	-	Troeberg et al., 1996
Z-Arg-Arg-NHMec			Z-Arg-Arg+NHMec	S		-	Z	Arg	Arg	AMC	-	-	-	Troeberg et al., 1996
Z-Phe-Arg-NHMec			Z-Phe-Arg+NHMec	S		-	Z	Phe	Arg	AMC	-	-	-	Troeberg et al., 1996