Nucleosome with an SSB at SHL -2.8 in complex with human PARP2 and HPF1, Class 1

Nucleosome with an SSB at SHL -2.8 in complex with human PARP2 and HPF1, Class 2

Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10)

NTSR1-G11-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State 3DVA Separated 1 (C-Closed-GTP)

NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State, 3DVA Sorted (C-Closed*-GTP)

NTSR1-G11-NTS(8-13) Complex in the Canonical, AHD Partially Closed State (C-P-Closed-Apo)

NTSR1-G11-NTS(8-13) Complex in the Canonical, AHD Open State (C-Open-Apo)

NTSR1-Gi-NTS(8-13) Complex in the Canonical, AHD Closed State (C-Closed-Apo)

NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Non-Canonical, AHD Closed State (NC-Closed-GTP)

NTSR1-Gi-NTS(8-13), GTP-bound Complex in the Canonical, AHD Open State (C-Open-GTP)

NTSR1-Gi-NTS(8-13) Complex in the Canonical, AHD Open State (C-Open-Apo)

NTSR1-G11-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State 3DVA Separated 2 (C-Closed*-GTP)

NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Non-Canonical, AHD Open State (NC-Open-GTP)

NTSR1-G11-NTS(8-13) Complex in the Non-Canonical, AHD Open State (NC-Open-Apo)

NTSR1-Gi-NTS(8-13) Complex in the Non-Canonical, AHD Open State (NC-Open-Apo)

Cryo-EM structure of raiA motif RNA from Thermosediminibacter oceani

NTSR1-Gi-NTS(8-13), GTP-bound Complex in the Canonical, AHD Open State (C-Open-GTP), MSP1D1

NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State (C-Closed-GTP), MSP1D1 Nanodisc

NTSR1-Gi-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State (C-Closed-GTP)

mouse PDCD5-TRiC complex

type II Lamassu, LmuACB from Vibrio cholerae O1 El

Homotrimer of the extracellular PPIase Mpn444 from Mycoplasma pneumoniae

mouse PDCD5-TRiC complex

type II Lamassu, LmuACB with DNA

type II Lamassu, LmuA tetramer

type II Lamassu, LmuACB from Vibrio cholerae O1 El

mouse PDCD5-TRiC complex

Cryo-EM structure of the cage-top domain of the erlin1/2 complex purified using GDN and CHS

mouse PDCD5-TRiC complex

A549 cell late endosome containing influenza A virus Pt44

A549 cell late endosome containing influenza A virus Pt47_1

A549 cell late endosome containing influenza A virus

A549 cell late endosome containing influenza A virus

A549 cell late endosome containing influenza A virus Pt52

A549 cell late endosome containing influenza A virus

A549 cell late endosome containing influenza A virus Pt38

Focused refinement of beta-barrel assembly machine from Escherichia coli in an late state of LptD assembly

Consensus refinement of beta-barrel assembly machine from Escherichia coli in an late state of LptD assembly

Reconstituted TRRAP lobe of the human TIP60 complex, distal region (focused refinement)

Cryo-EM structure of the Nipah Virus nucleocapsid complex

SsoPfMCM:DNA class 1a from merged particles

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 1, Consensus map

CryoEM structure of computationally designed bundlemer peptide nanotube (14 protofilament)

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 2, Focused map

CryoEM structure of computationally designed bundlemer peptide nanotube (15 protofilament)

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 1, Focused

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 2, Consensus map

SsoPfMCM:DNA class 2b from merged particles

SsoPfMCM:DNA class 1c from merged particles

Cryo-EM structure of the reconstituted TRRAP lobe of the human TIP60 complex (consensus map filtered by local resolution)

SsoPfMCM:DNA class 2b from DNA 1

SsoPfMCM:DNA class 1b from DNA 1

Reconstituted TRRAP lobe of the human TIP60 complex, top region (focused refinement)

SsoPfMCM:DNA class 1a from DNA 1

SsoPfMCM:DNA class 1b from merged particles

Reconstituted RuvBL lobe of the human TIP60 complex, top RUVBL region (focused refinement)

Reconstituted RuvBL lobe of the human TIP60 complex, bottom RUVBL region (focused refinement)

Cryo-EM structure of the reconstituted RuvBL lobe of the human TIP60 complex (consensus map filtered by local resolution)

Reconstituted RuvBL lobe of the human TIP60 complex, HSA module (focused refinement)

SsoPfMCM:DNA class 2a from DNA 1

SsoPfMCM:DNA class 2a from merged particles

Reconstituted TRRAP lobe of the human TIP60 complex, core region (focused refinement)

SsoPfMCM:DNA class 3 from merged particles

SsoPfMCM:DNA class 3 from DNA 1

SsoPfMCM:DNA class 1c from DNA 1

Reconstituted TRRAP lobe of the human TIP60 complex, bottom region (focused refinement)

RuvBL lobe of the native human TIP60 complex, ATPase module (focused refinement)

SK5A-Matured glycine/glutamate in complex with GluN1-GluN2B, full refinement

SK3D-Germline in complex with GluN1-GluN2B, full refinement

SK5G-Germline

SK3D-Matured in complex with GluN1-GluN2B, full refinement

SK5G-Matured in complex with GluN1-GluN2B, full refinement

OX1-Germline in complex with GluN1-GluN2B, full refinement

SK5B-Matured in complex with GluN1-GluN2B, full refinement

OX1-Matured in complex with GluN1-GluN2B, full refinement

SK5A-Germline in complex with GluN1-GluN2B, full refinement

SK5B-Germline in complex with GluN1-GluN2B, full refinement

SK5A-Matured apo state in complex with GluN1-GluN2B, full refinement

Cryo-EM structure of the E. coli ArnA hexamer

Cryo-EM structure of the GLP-1-bound human GLP-1R-Gq complex

Cryo-EM structure of the Vo domain of V/A-ATPase in liposomes under no pmf condition,state2

Cryo-EM structure of the Vo domain of V/A-ATPase in liposomes under no pmf condition,state3

Egalitarian-BicD in complex with K10 TLS RNA (Structure E)

Egalitarian-BicD in complex with K10 TLS RNA (Structure C)

Egalitarian-BicD in complex with hSL1 and hSL2 of the hairy localization element

Egalitarian-BicD in complex with K10 TLS RNA (Structure B)

Egalitarian-BicD in complex with K10 TLS RNA (Structure D)

Egalitarian-BicD in complex with GLS of gurken mRNA

Egalitarian-BicD in complex with ILS of I-factor mRNA (Structure B)

Egalitarian-BicD in complex with hSL1 of the hairy localization element (Structure C)

Egalitarian-BicD in complex with bcdSLV of bicoid mRNA (Structure C)

Egalitarian-BicD in complex with ILS of I-factor mRNA (Structure A)

Egalitarian-BicD in complex with K10 TLS RNA (Structure A)

Desmotubule-coating assembly in protonemata of GHL17 Physcomitrium patens,centered on assembly surface

Egalitarian-BicD in complex with bcdSLV of bicoid mRNA (Structure B)

Egalitarian-BicD in complex with hSL1 of the hairy localization element (Structure B)

Egalitarian-BicD in complex with hSL1 of the hairy localization element (Structure A)

Egalitarian-BicD in complex with bcdSLV of bicoid mRNA (Structure A)

Cryo-ET of a plasmodesma in wild type Physcomitrium patens protonema tissue treated with abscisic acid

Cryo-ET of a plasmodesma in wild type Physcomitrium patens protonema tissue treated with abscisic acid

Cryo-ET of a plasmodesma in GHL17 Physcomitrium patens protonema tissue

Cryo-ET of a plasmodesma in wild type Physcomitrium patens protonema tissue

Adenovirus dodecahedron

C1 CHIMPSELS_S57C ADDomer map.

Cryo-EM structure of alphaM/beta2:C3d-anti-CR3-Nb headpiece complex (HPO1 3D class reconstruction)

Cryo-EM structure of alphaM/beta2:C3d-anti-CR3-Nb headpiece complex (HPO2 3D class reconstruction)

Cryo-EM structure of alphaM I-domain:C3d-anti-CR3-Nb complex focused refinement from the alphaM/beta2:C3d-anti-CR3-Nb headpiece complex

Cryo-EM structure of mutant R61H alphaM/beta2 headpiece complex

I4 map of CHIMPSELS_S57C full ADDomer.

Cryo-ET of a plasmodesma in wild type Physcomitrium patens gametophore leaflet tissue

Cryo-ET of a plasmodesma in GHL17 Physcomitrium patens protonema tissue

Cryo-ET of a plasmodesma in wild type Physcomitrium patens gametophore leaflet tissue

Cryo-ET of a plasmodesma in wild type Physcomitrium patens protonema tissue

Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain)

Engineering the ADDomer Nanoparticle Vaccine Scaffold for Improved Assembly and Enhanced Stability.

human GM-CSF with Fabs from autoantibodies, F1 and BD.

human GM-CSF with Fabs from autoantibodies, F1 and C.

Cryo-EM structure of the complex CDK16:CCNY:14-3-3

Cryo-EM structure of the complex CCNY:14-3-3

Human TRPM8 fully-swapped, ligand-free structure in the absence of calcium at 4 degrees Celsius resolved in cell vesicles

Avian TRPM8 (Parus major) fully-swapped, closed, ligand-free in the presence of calcium, structure resolved in cell vesicles

Avian TRPM8 (Parus major) fully swapped closed, calcium free, in the presence of menthol, resolved in cell vesicles

Avian TRPM8 (Parus major) semi-swapped, closed, calcium free, menthol bound structure resolved in cell vesicles

Human TRPM8 menthol bound structure at 4 degrees Celsius resolved in cell vesicles using cryo-EM

Avian TRPM8 (Parus major) semi-swapped, ligand-free structure resolved in cell vesicles using cryo-EM

Avian TRPM8 (Parus major) semi-swapped, ligand-free structure at high pH and 4 degrees Celsius resolved in GDN using cryo-EM

Avian TRPM8 (Parus major) semi-swapped, closed, ligand-free in the presence of calcium, structure resolved in cell vesicles

Human TRPM8 closed, ligand-free structure resolved in GDN using cryo-EM

CryoEM structure of the GSDME pore, C27

Avian TRPM8 (Parus major) closed, ligand-free structure resolved in cell vesicles using cryo-EM

Human TRPM8 V915Y fully-swapped, closed, ligand-free structure resolved in GDN

Human TRPM8 fully-swapped, desensitized, ligand-free structure at 4 degrees Celsius resolved in cell vesicles

Parus major TRPM8 with a chimeric human outer pore loops, semi-swapped, ligand-free, cold, structure resolved in GDN

Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 1 (A)

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 4

Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 1 (B)

Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 1

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 3

Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 4

Cryo-EM structure of Human UBA1-UBE2O-Ub -Recruitment state 1 (consensus map)

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 2

Cryo-EM structure of depolymerase S2-4 from Klebsiella phage K64-1

Cryo-EM structure of depolymerase S2-4 from Klebsiella phage K64-1

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 1

Cryo-EM density map of the 96-nm repeat of the human respiratory doublet microtubule

Cryo-EM density map of the 48-nm repeat of the CCDC114-mutant PCD patient respiratory doublet microtubule with c.705_706insGCAG mutation

Cryo-EM density map of the 48-nm repeat of the human respiratory doublet microtubule

Cyro-EM density map of the 96-nm repeat of the CCDC114-mutant PCD patient respiratory doublet microtubule with c.-41-2A>C mutation

Cryo-EM structures of the Azoarcus pre-tRNA(ILE) intron conformation after the cyclization

Cryo-EM structures of the Azoarcus pre-tRNA(ILE) conformation a undergoing the first-step self-splicing

Cryo-EM structures of the Azoarcus pre-tRNA(ILE) conformation b undergoing the first-step self-splicing

Cryo-EM structures of the Azoarcus pre-tRNA(ILE) intron conformation after the self-splicing

Cryo-EM density map of the 48-nm repeat of the CCDC114-mutant PCD patient respiratory doublet microtubule with c.-41-2A>C mutation

Cryo-EM structure of the Azoarcus sp. BH72 pre-tRNA(ILE) intron after second-step cyclization (circular form)

Open-state structure of veratridine-activated human Nav1.7

Structure of HN HA at pH 7.0 (conformation2).

Structure of HN-113S HA at pH 7.0.

Structure of HN HA at pH 6.4 (conformation3).

Cryo-EM structure of AtABCC2 in apo form

Cryo-EM structure of dimeric AtABCC2

Cryo-EM structure of the hGPR4-apo Receptor in pH 7.8

Structure of HN HA at pH 6.4 (conformation4).

Structure of HN-113S HA at pH 6.4.

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation1-composite-1

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation1-composite-2

CryoEM Structure of LmuAB Apo State

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation 2

Substrate-engaged human 26S proteasome bound to midnolin with RPT1 at top of spiral staircase

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation1

CryoEM Structure of LmuAB-DNA complex

Substrate-engaged human 26S proteasome bound to midnolin with RPT2 at top of spiral staircase

Focused refinement of RPN1 and the C-terminal helix of midnolin in the substrate-engaged human 26S proteasome

Cryo-EM structure of AZ-GS bound AtABCC2

Focused refinement of 19S in the substrate-engaged human 26S proteasome bound to midnolin with RPT6 at top of spiral staircase

Substrate-engaged human 26S proteasome bound to midnolin with RPT5 at top of spiral staircase

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-dimer conformation

reduced NorQ-NorD VWA domain complex from Paracoccus denitrificans

NorQ in complex with NorD VWA domain steep staircase subset 2 from Paracoccus denitrificans

NorQ in complex with NorD VWA domain from Paracoccus denitrificans

NorQD complex state 4 from Jhaorihella thermophila

NorQ in complex with NorD VWA domain steep staircase subset 1 from Paracoccus denitrificans

NorQ hexamer from Paracoccus denitrificans

NorQD complex state 1 from Jhaorihella thermophila

NorQD complex state 3 from Jhaorihella thermophila

Tetrameric cystathionine beta-synthase of Mycobacterium tuberculosis bound to AOAA

Tetrameric cystathionine beta-synthase of Mycobacterium tuberculosis bound to O-Benzylhydroxylamine

Structural mechanism of substrate binding of the human Proline Transporter

Structure of the apo-state human proline transporter purified in DDM buffer

Structure of the intial complex in filament assembly at 3.23 angstroms resolution, conformation 2.

Cryo-EM structure of the erlin1/2 complex purified using DDM and GDN

Cryo-EM structure of the erlin1/2 complex purified using GDN and CHS

The LBD-TMD structure of GluA4-1D8 complex

Cryo-EM overall structure of the erlin1/2 complex purified using GDN and CHS

Structure of the cholesterol-bound human proline transporter purified in DDM buffer

The GluA4-ATD in Complex with the 1D8-Fab

Structure of the L-proline-free human proline transporter purified in DDM buffer

Structure of the apo-state human proline transporter purified in DDM/CHS buffer

Structure of the L-proline-free human proline transporter purified in DDM/CHS buffer

Structure of the cholesterol-bound human proline transporter purified in DDM/CHS buffer

Cryo-EM overall structure of the erlin1/2 complex purified using DDM and GDN

Cryo-EM structure of the cage-top domain of the erlin1/2 complex purified using DDM and GDN

The ATD structure of homomeric GluA4 AMPA receptor

The LBD-TMD structure of homomeric GluA4 AMPA receptor

Human Serum Albumin in complex with four nanobodies: nb118, nb68, N30 & N23

Human Serum Albumin in complex with four nanobodies: nb33, nb77, nb125 & N42

Human Serum Albumin in complex with four nanobodies: N33, nb139, nb39 & nb104

Rubisco subtomogram average from chloroplasts of two weeks old Physcomitrium patens protonemata cells.

Cryo-electron tomograms of Arabidopsis thaliana embryos.

F-actin decorated by ITPKA

Cryo-EM structure of apo form of Arthrobacter psychrolactophilus L-arabinose isomerase

NorQD complex state 2 from Jhaorihella thermophila

Cryo-electron tomograms of Physcomitrium patens phyllids.

Structure of the YbjP lipoprotein bound to the MacAB-TolC tripartite efflux pump

Cryo-electron tomograms of Limonium bicolor salt gland.

Photosystem II from Arabidopsis thaliana

Porcine ATP synthase with inhibitory protein IF1, Peripheral Stalk domain, DP-state

Porcine ATP synthase with inhibitory protein IF1, F1 domain, DP-state

Porcine ATP synthase with inhibitory protein IF1, Fo domain, DP-state

Porcine ATP synthase without inhibitory protein IF1, F1 domain, DP-state

Porcine ATP synthase without inhibitory protein IF1, Peripheral Stalk domain, DP-state

Porcine ATP synthase without inhibitory protein IF1, Fo domain, DP-state

Porcine ATP synthase with inhibitory protein IF1, E-state

Human Serum Albumin in complex with four nanobodies: N33, nb139 & nb104

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation C-terminal Domain Locally Refined Map

Structure of GPR61 bound to inverse agonist compound 15

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Consensus Map

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Transmembrane Domain (C4) Locally Refined Map

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation BSol Locally Refined Map

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation N-terminal Domain Locally Refined Map

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 1

Sub-tomogram averaged structure of the Tad pilus secretin in Caulobacter crescentus

Sub-tomogram averaged structure of the non-piliated Tad machine in Caulobacter crescentus

Sub-tomogram averaged structure of the piliated Tad machine in Caulobacter crescentus

Nucleosome with an SSB at SHL -2.8 in complex with the WGR domain of human PARP2, Class 2