EMD-74042

Single-particle
3.65 Å
EMD-74042
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Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74042
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Human TRPM8 fully-swapped, desensitized, ligand-free structure at 4 degrees Celsius resolved in cell vesicles

EMD-74042

Single-particle
3.65 Å
EMD-74042
3D View Gallery
Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric complex of human TRPM8 determined in cell-derived vesicles.
Fitted models: 9zcv

Deposition Authors: Choi KY, Lin X, Cheng Y, Julius D
Structural energetics of cold sensitivity
Choi KY, Lin X, Cheng Y, Julius D
(2026) Nature
DOI: doi:10.1038/s41586-026-10276-2
ISSN: 1476-4687
ASTM: NATUAS