EMD-75112

Single-particle
3.7 Å
EMD-75112
3D View Gallery
Deposition: 15/01/2026
Map released: 25/03/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75112

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-10en summary report (pdf.gz) Map-10en FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

SK3D-Matured in complex with GluN1-GluN2B, full refinement

EMD-75112

Single-particle
3.7 Å
EMD-75112
3D View Gallery
Deposition: 15/01/2026
Map released: 25/03/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: SK3D IgG in complex with GluN1-GluN2B NMDAR protein
Fitted models: 10en

Deposition Authors: Kleeman SO, Furukawa HF
Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity.
Kleeman SO, Michalski K, Zhao X , Steigerwald R, Ferrer M, Levett L, Ertel E, Schultz A , Simorowski N, Moody P, Wee TL , Valente C, Fox S, Makuch M, Thomsen S, Harrison R , Regan C , Preall J , Gao Q, Thomas D , Habel J, Rubino R, Irani S , Furukawa H , Janowitz T
(2026) Nature , 653 , 1216 - 1228
PUBMED: 41882353
DOI: doi:10.1038/s41586-026-10278-0
ISSN: 1476-4687
ASTM: NATUAS