EMD-55599

Single-particle
3.1 Å
EMD-55599
3D View Gallery
Deposition: 06/11/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55599

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9t5z summary report (pdf.gz) Map-9t5z FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of alphaM/beta2:MEM148-Fab headpiece complex (without alphaM I-domain)

EMD-55599

Single-particle
3.1 Å
EMD-55599
3D View Gallery
Deposition: 06/11/2025
Map released: 25/03/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Headpiece of alphaM/beta2 in complex with MEM148 Fab
Fitted models: 9t5z

Deposition Authors: Lorentzen J , Andersen GR
Three cryo-EM structures of complement C3d-bound alpha M beta 2 reveal an unexpected layer of dynamics for alpha I-containing integrin receptors.
Lorentzen J , Fruergaard MU, Lukacsi S, Jorgensen MH, van Veghel TLG, Jensen RK, Pietrzak-Lichwa KJ, Bajtay Z, Horejsi V, Flygaard RK, Vorselen D, Mortensen SA, Andersen GR
(2026) Sci Adv , 12 , eaea7241 - eaea7241
PUBMED: 42102216
DOI: doi:10.1126/sciadv.aea7241
ISSN: 2375-2548
Grant Support: