EMD-74041

Single-particle
2.86 Å
EMD-74041
3D View Gallery
Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74041

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zcu summary report (pdf.gz) Map-9zcu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human TRPM8 V915Y fully-swapped, closed, ligand-free structure resolved in GDN

EMD-74041

Single-particle
2.86 Å
EMD-74041
3D View Gallery
Deposition: 24/11/2025
Map released: 25/03/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric complex of human TRPM8 V915Y determined in a cell-derived vesicles.
Fitted models: 9zcu

Deposition Authors: Choi KY, Lin X, Cheng Y , Julius D
Structural energetics of cold sensitivity.
Choi KY, Lin X, Cheng Y , Julius D
(2026) Nature , 653 , 962 - 970
PUBMED: 41882351
DOI: doi:10.1038/s41586-026-10276-2
ISSN: 1476-4687
ASTM: NATUAS