EMD-75138

Single-particle
4.46 Å
EMD-75138
3D View Gallery
Deposition: 16/01/2026
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75138
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 10fo summary report (pdf.gz) Map and 10fo FULL report (pdf.gz)
EMICSS annotations (xml)

SK5B-Germline in complex with GluN1-GluN2B, full refinement

EMD-75138

Single-particle
4.46 Å
EMD-75138
3D View Gallery
Deposition: 16/01/2026
Map released: 25/03/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: SK5B-Germline IgG in complex with GluN1-GluN2B NMDAR protein
Fitted models: 10fo

Deposition Authors: Kleeman SO, Furukawa HF
Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity.
Kleeman SO, Michalski K, Zhao X , Steigerwald R, Ferrer M, Levett L, Ertel E, Schultz A , Simorowski N, Moody P, Wee TL , Valente C, Fox S, Makuch M, Thomsen S, Harrison R , Regan C , Preall J , Gao Q, Thomas D , Habel J, Rubino R, Irani S , Furukawa H , Janowitz T
(2026) Nature
PUBMED: 41882353
DOI: doi:10.1038/s41586-026-10278-0
ISSN: 1476-4687
ASTM: NATUAS