EMD-74124

Single-particle
3.71 Å
EMD-74124
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Deposition: 01/12/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74124
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Human TRPM8 fully-swapped, ligand-free structure in the absence of calcium at 4 degrees Celsius resolved in cell vesicles

EMD-74124

Single-particle
3.71 Å
EMD-74124
3D View Gallery
Deposition: 01/12/2025
Map released: 25/03/2026
Last modified: 25/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homotetrameric complex of human TRPM8 determined in cell-derived vesicles.
Fitted models: 9zf0

Deposition Authors: Choi KY, Lin X, Cheng Y, Julius D
Structural energetics of cold sensitivity
Choi KY, Lin X, Cheng Y, Julius D
(2026) Nature
DOI: doi:10.1038/s41586-026-10276-2
ISSN: 1476-4687
ASTM: NATUAS