Fab fragment of Antibody with NiV glycoprotein F

ML418 bound inwardly rectifying potassium channel Kir7.1 R162Q mutant

C3 reconstruction of the thermophilic bacteriophage P74-26 Neck

HIV-1 CH505.N197D Env Ectodomain (Immature VLPs)

HIV-1 ADA.CM Env

HIV-1 Env BG505.SOSIP

Motor domain of human dynein-1 in pre-power stroke bound to dynactin-p150glued-CC1B-ICD and LIS1

Mitochondrial Creatine Kinase in complex with ADP, creatine, and uncompetitive inhibitor uci

HIV-1 ADA.CM.755* (Immature VLPs, Triton X-100 extracted)

Motor domain of human dynein-1 in post1 state

Asymmetric reconstruction of filled phage capsids lacking neck and tail

Motor domains of phi-like human dynein-1 bound to dynactin-p150glued and LIS1

Motor domain of human dynein-1 in pre-power stroke bound to dynactin-p150glued-CC1B and LIS1

12.7-Angstrom resolution structure of bacteriophage Sf6 in the C1 symmetry by cryo-electron tomography and sub-tomogram averaging with 538 particles reveal the tail appendage

Asymmetric reconstruction of filled phage capsids with broken tails

Mitochondrial Creatine Kinase in complex with ADP and uncompetitive inhibitor uci

HIV-1 CH505.N197D Env Ectodomain (Mature VLPs)

Full-length human cytoplasmic dynein-1 in phi-like state bound to dynactin-p150glued and LIS1

HIV-1 ADA.CM.755* Env (Immature VLPs)

HIV-1 BG505.755* Env

HIV-1 ADA.CM.755* Env (Immature VLPs, tilted class)

C5 reconstruction of the thermophilic bacteriophage P74-26 Portal Vertex

Composite reconstruction of the thermophilic bacteriophage P74-26 Neck and Portal Vertex

Cryo-EM structure of the DDB1/CRBN-MRT-5702-G3BP2 ternary complex

Dynactin and dynein-1 tail region of dynein-dynactin complex on microtubule in the presence of LIS1

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (head structure)

9.1-Angstrom resolution structure of the portal protein core of bacteriophage Sf6 by cryo-electron tomography and sub-tomogram averaging with 538 particles

Human Oct4 bound to nucleosome reconstituted with human histones and 182 bp human LIN28B sequence

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (body structure)

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (consensus structure)

Cryo-EM structure of F-box helicase 1 (FBH1) bound to an SCF ubiquitin ligase complex and a 3-way DNA fork (substrate structure)

Structure of the distal part of the bacteriophage T4 tail

Focused refinement map of the human M4 muscarinic acetylcholine receptor bound to the bitopic agonist C110

Human M4 muscarinic acetylcholine receptor Gi1 complex (mini-Gsi chimera) bound to the bitopic agonist C110

cryo-ET subtomogram-averaged structure of mouse heavy-chain apoferritin resolved at 2.71 Angstroms

Human TRPM4 ion channel in MAASTY copolymer lipid nanodisc in a calcium-bound state

Structure of the bacterial archaellum from L. aerophila

cryo-EM map of the human mPSF with FIP1

Open state of A8 gpJ 713 central tail fiber with OmpC G17 from E. coli EDL933

Closed state of A8 gpJ 713 central tail fiber

Human KCNQ2-CaM in complex with QO-58 and PIP2

Human KCNQ2-CaM in complex with QO-83 and PIP2

cryo-EM strucutre of CPSF160-WDR33-ZC3H18

Supercoiling bacterial archaellum filament from L. aerophila

Methanosarcina acetivorans 70S ribosome in complex with SriA and SriB composite map

Methanosarcina acetivorans 70S ribosome in complex with SriD composite map

Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD 30S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD 30S head focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD consensus map

Methanosarcina acetivorans 70S ribosome in complex with SriA and SriB consensus map

Methanosarcina acetivorans 70S ribosome in complex with SriA and SriB 50S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriD 30S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD 50S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriA and SriB 30S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriD consensus map

Methanosarcina acetivorans 70S ribosome in complex with SriD 50S focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriA and SriB 30S head focused refinement

Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD composite map

Structure of Stalled Beta-Galactosidase 70S Ribosome Nascent Chain

CryoEM structure of Aldehyde dehydrogenase from Francisella tularensis subsp. tularensis at 3.03A resolution

HDAg complex with 86-pRNA, Body1

HDV particle subtomogram reconstruction

Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Composite Map

Twisted arrangement of the HDV 311-RNP, Multibody refinement, Body 1

Linear arrangement of the HDV 311-RNP

Twisted arrangement of the HDV 311-RNP

HDAg complex with 86-pRNA, Body2

Structure of human PADI6-UHRF1-UBE2D3 complex

Cryo-EM structure of the apo-ConsOR5-Gs complex

Consensus olfactory receptor bmOR6A2 in complex with mini-Golf trimeric protein

Consensus olfactory receptor consOR6 in complex with mini-Golf trimeric protein

Consensus olfactory receptor bmOR6A2 in complex with mini-Golf trimeric protein

Consensus olfactory receptor bmOR6A2 in complex with mini-Golf trimeric protein

Consensus olfactory receptor consOR6 bound to alpha-hexyl cinnamaldehyde and in complex with mini-Golf trimeric protein

Consensus olfactory receptor consOR6 in complex with Gs trimeric protein

Consensus olfactory receptor consOR6 in complex with mini-Golf trimeric protein

Structure of the H4.V variant nucleosome core particle from Trypanosoma brucei

NTD of SARS-CoV-2 Delta variant Spike in complex with Fab854

Structure of the H3.V-H4.V variant nucleosome core particle from Trypanosoma brucei

Active substate 3 of the GluA4 homotetramer.

Active substate 1 of the GluA4 homotetramer.

Activated GluA4 homotetrameric AMPAR.

Active substate 2 of the GluA4 homotetramer.

Active substate 4 of the GluA4 homotetramer.

Active substate 5 of the GluA4 homotetramer.

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with Ponesimod

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with HY-X-1011

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with CYM5442

Cryo-EM structure of Gi coupled Sphingosine 1-phosphate receptor bound with SAR247799

Cryo-EM structure of rice PHS1-DPE1 complex

Cryo-EM structure of rice PHS1 dimer

Cryo-EM structure of rice DPE1 dimer

Cryo-EM structure of human V1aR bound with atosiban at a resolution of 2.8 angstrom

MscS in Glyco-DIBMA Native Nanodiscs (C7 symmetry)

Stable open sheep connexin-46/50 in amphipol at low pH

Gated state sheep connexin-46/50 in DMPC nanodiscs at neutral pH

Stable open state sheep connexin-46/50 in DMPC nanodiscs at neutral pH

Destabilized open state sheep connexin-46 in DMPC nanodiscs at neutral pH

Stable open state sheep connexin-46/50 in DMPC nanodiscs at low pH

Ammonia monooxygenase in native membranes from N. briensis

Asymmetrically gated state sheep connexin-46/50 in DMPC nanodiscs at low pH

Gated state sheep connexin-46/50 in DMPC nanodiscs at low pH

Destabilized open state sheep connexin-46/50 in DMPC nanodiscs at low pH

Cryo-EM structure of SARS-CoV-2 JN.1 RBD in complex with F61R2-780 Fab

Cryo-EM structure of SARS-CoV-2 JN.1 spike glycoprotein in complex with F61R2-780 Fab

Cryo-EM structure of human SOD1 (G93A) amyloid filament

protein structure of DDB1-DDA1-DET1-Ube2e2 complex

Cryo-EM structure of SARS-CoV-2 KP.3.1.1 RBD in complex with F61R2-780 Fab

Cryo-EM structure of DDB1-DDA1-DET1 complex

protein structure of DDB1-DDA1-DET1

Cryo-EM structure of DDB1-DDA1-DET1 complex

DDB1-DDA1-DET1-Ube2e2-COP1-c-Jun-STK40 complex

Cryo-EM structure of SARS-CoV-2 KP.3.1.1 spike glycoprotein in complex with F61R2-780 Fab

Cryo-EM structure of DDB1-DDA1-DET1-Ube2e2 complex

Local refinement of stacked like DDB1-DDA1-DET1-Ube2e2-COP1 complex (layer 1)

protein structure of DDB1-DDA1-DET1-Ube2e2 bound to COP1 dimer

Local refinement of stacked like DDB1-DDA1-DET1-Ube2e2-COP1 complex (layer 2)

Cryo-EM structure of dimeric DDB1-DDA1-DET1-Ube2e2-COP1 complex

Consensus refinement: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homo dimers of Akirin-2. Focussed refinement

Cryo-EM structure of the Chromera velia PSI supercomplex at 1.84 Angstrom resolution

Structure of E.coli ribosome with nascent chain at linker length of 31 amino acids, with mRNA, P-site and A-site tRNAs

Yeast pre-60S Domain II intermediate

Local Refinement of human M4 muscarinic acetylcholine receptor G protein complex bound to selective PAM Emraclidine

CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATE

Composite map: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2

Structural characterisation of chromatin remodelling intermediates supports linker DNA dependent product inhibition as a mechanism for nucleosome spacing.

Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2 - focussed refinement on Importin-9 and Akirin-2

Binary complex of human Importin-9 with one homodimer of Akirin-2

Structural characterisation of chromatin remodelling intermediates supports linker DNA dependent product inhibition as a mechanism for nucleosome spacing.

Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2 - focussed refinement on the alpha subunits, Ipo-9 and Ak2

Cryo-EM structure of the E3 ligase HECTD3 conjugated to ubiquitin

Cryo-EM structure of the E3 ligase HECTD3

S. islandicus CdvA filament (cryo-EM)

CdvB2 filament - high twist, class B

Cerebellar GluA1/4 NTD tetramer (focused refinement)

CdvB2 filament - low twist

Cryo-EM structure of the catalytic core of human telomerase at the elongation state of the repeat addition cycle

Cryo-EM structure of the catalytic core of human telomerase at the initiation state of the repeat addition cycle

Cryo-EM structure of the E3 ligase HECTD3

CdvB2 filament - high twist, class A

Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle

Noc2-TAP pre-60S particle - state 1

Asymmetric hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis with "short" coiled-coil domain

Symmetric hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis

Asymmetric hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis with "long" coiled-coil domain

Noc2-TAP 90S particle - state A3

Noc2-TAP 90S particle - state A2

Noc2-TAP 90S particle - state A1

Noc2-TAP pre-60S particle - state 3

Cryo-EM structure of SFTSV Gn in complex with ZS01S-336

Cryo-EM structure of SFTSV Gn in complex with ZS004-1C5

SFP21A phage tail fiber (Gp09)

Cryo-EM structure of SFTSV Gn in complex with ZS01S-65

LGP2:dsRNA complex

LGP2:MDA5:dsRNA filament

TamAB hybrid barrel state

TamAB in non-hybrid barrel state

Structure of SID-1 in complex with dsRNA (dodecameric form)

Human Kv1.3-H451V with A0194009G09 nanobodies conformation 2

Human Kv1.3-H451V with A0194009G09 nanobodies conformation 1

Human Kv1.3 mutant-H451V

Human Kv1.3 mutant-P424G

6-fold-symmetric reconstruction focused on the middle part of the bacteriophage T4 tail

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-S complex, monomeric form

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-S complex, tetrameric form

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-B complex, protomer A focused refinement

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-B complex, dimeric form

6-fold-symmetric reconstruction focused on the bacteriophage T4 baseplate

6-fold-symmetric reconstruction focused on the bacteriophage T4 neck region

Structure of the middle part of the bacteriophage T4 tail

Structure of the bacteriophage T4 portal-neck-tail connector complex

In situ cryo-electron tomogram of 4days WT cytoplasm 2

The structure of FIPV spike glycoprotein

In situ cryo-electron tomogram of 4days WT nucleus (trimer close to NE)

In situ cryo-electron tomogram of 1day WT nucleus

In situ cryo-electron tomogram of 4days rpn9deltaN nucleus

In situ cryo-electron tomogram of 4days WT cytoplasm 1

In situ cryo-electron tomogram of 4days rpn13null nucleus

In situ cryo-electron tomogram of 4days rpn2deltaN nucleus

26S proteasome trimer

Cryo-EM structure of human lipid phosphate phosphatase 1 complexed with PO4 in nanodiscs

In situ cryo-electron tomogram of 4days WT nucleus (PSG at NE)

26S proteasome trimer close to nuclear envelope

human Betaine/GABA transporter 1 in complex with Betaine

In situ cryo-electron tomogram of 4days WT cell

In situ cryo-electron tomogram of 18h nucleus

human Betaine/GABA transporter 1 in complex with GABA

human Betaine/GABA transporter 1 in inward facing conformation

Cryo-EM structure of Fab-Gn Head-Linker-Gn Head complex

Twenty-two polymer Msp1 from S.cerevisiae(with a catalytic dead mutation) in complex with an unknown peptide substrate

Sixteen polymer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate

Tilvestamab Fab bound to the anti-Fab nanobody

Pentamer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate state2

Cryo-EM consensus map of Bovine lactoferrin in TBS buffer

Cryo-EM structure of EBV gH/gL/gp42 in complex with fab 4G12

STRUCTURE OF UNSTACKED C2S2-TYPE PSII-LHCII SUPERCOMPLEX FROM PISUM SATIVUM

CGRP Receptor in complex with C8 Minibinder

dsDNA in the central channel of the bacteriophage P74-26 neck

Mus musculus TASK-1 (KCNK3) in MSP1E3D1 lipid nanodisc at pH 6.0 and 100 mM KCl

C12 reconstruction of the thermophilic bacteriophage P74-26 Neck

C3 reconstruction of the thermophilic bacteriophage P74-26 Capsid-less Neck

R162Q mutant of inwardly rectifying potassium channel Kir7.1

C12 reconstruction of the thermophilic bacteriophage P74-26 Collar-less Neck

Honeybee silk hetereotetramer coiled coil

C1 reconstruction of the thermophilic bacteriophage P74-26 Portal and Portal Vertex