EMD-70791

Single-particle
2.5 Å
EMD-70791
3D View Gallery
Deposition: 23/05/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70791
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9os2 summary report (pdf.gz) Map and 9os2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the DDB1/CRBN-MRT-5702-G3BP2 ternary complex

EMD-70791

Single-particle
2.5 Å
EMD-70791
3D View Gallery
Deposition: 23/05/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DDB1/CRBN-MRT-5702-G3BP2 ternary complex
Fitted models: 9os2

Deposition Authors: Quan C, Petzold G, Gainza P, Tsai J, Bunker RD, Wiedmer L, Donckele EJ
Cereblon induces G3BP2 neosubstrate degradation using molecular surface mimicry
Annunziato S, Quan C, Donckele EJ, Lamberto I, Bunker RD, Zlotosch M, Schwander L, Murthy A, Wiedmer L, Staehly C, Matysik M, Gilberto S, Kapsitidou D, Wible D, de Donatis GD, Trenh P, SriRamaratnam R, Strande V, Almeida R, Dolgikh E, DeMarco B, Tsai J, Sadok A, Zarayskiy V, Walter M, Tiedt R, Lumb KJ, Bonenfant D, Fasching B, Castle JC, Townson SA, Petzold G, Gainza P
(2026) Nat Struct Mol Biol
DOI: doi:10.1038/s41594-025-01738-8
ISSN: 1545-9985
Grant Support: