EMD-49554

Single-particle
3.5 Å
EMD-49554
3D View Gallery
Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49554

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nms summary report (pdf.gz) Map-9nms FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

R162Q mutant of inwardly rectifying potassium channel Kir7.1

EMD-49554

Single-particle
3.5 Å
EMD-49554
3D View Gallery
Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: potassium channel tetramer of four identical subunits of inwardly rectifying potassium channel Kir7.1
Fitted models: 9nms

Deposition Authors: Peisley A , Cone R

ML418 Binds in the Pore of the Inward Rectifier Kir7.1 and Inhibits the Channel In Vivo to Reduce Food Intake and Body Weight
Peisley A , Cone R
To Be Published
Grant Support: