EMD-49554

Single-particle
3.5 Å
EMD-49554
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Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49554
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nms summary report (pdf.gz) Map and 9nms FULL report (pdf.gz)
EMICSS annotations (xml)

R162Q mutant of inwardly rectifying potassium channel Kir7.1

EMD-49554

Single-particle
3.5 Å
EMD-49554
3D View Gallery
Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: potassium channel tetramer of four identical subunits of inwardly rectifying potassium channel Kir7.1
Fitted models: 9nms

Deposition Authors: Peisley A, Cone R

ML418 Binds in the Pore of the Inward Rectifier Kir7.1 and Inhibits the Channel In Vivo to Reduce Food Intake and Body Weight
Peisley A, Cone R
To Be Published
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