EMD-53246
Consensus refinement: Ternary complex of the human 20S proteasome in complex with Importin-9 and two homo dimers of Akirin-2. Focussed refinement
EMD-53246
Single-particle3.3 Å
Deposition: 25/03/2025Map released: 28/01/2026
Last modified: 25/03/2026
Sample Organism:
Homo sapiens
Sample: Ternary complex of the human 20S proteasome in complex with two dimers of Akirin-2 and Importin-9
Deposition Authors: Brunner HL
,
Grundmann L ,
Haslelbach D
Sample: Ternary complex of the human 20S proteasome in complex with two dimers of Akirin-2 and Importin-9
Deposition Authors: Brunner HL
,
Grundmann L ,
Haslelbach D
A multivalent adaptor mechanism drives the nuclear import of proteasomes.
Brunner HL ,
Kalis RW ,
Grundmann L ,
Hodakova Z ,
Koskova Z ,
Grishkovskaya I ,
de Almeida M,
Hinterndorfer M ,
Knaudt H ,
Hofflin S,
Andersch F ,
Kotisch H,
Dickmanns A,
Cuylen-Haering S ,
Zuber J ,
Haselbach D
(2026) Nat Commun , 17
,
Kalis RW ,
Grundmann L ,
Hodakova Z ,
Koskova Z ,
Grishkovskaya I ,
de Almeida M,
Hinterndorfer M ,
Knaudt H ,
Hofflin S,
Andersch F ,
Kotisch H,
Dickmanns A,
Cuylen-Haering S ,
Zuber J ,
Haselbach D
(2026) Nat Commun , 17
Grant Support:
- H2020 Marie Curie Actions of the European Commission: 847548 (European Union)
- Austrian Science Fund: 10.55776/F79 (Austria)