EMD-48385
CGRP Receptor in complex with C8 Minibinder
EMD-48385
Single-particle3.26 Å
Deposition: 19/12/2024Map released: 28/01/2026
Last modified: 12/08/2026
Sample Organism:
Homo sapiens,
synthetic construct
Sample: CGRP Receptor in complex with dC2_049
Fitted models: 9mm5
Deposition Authors: Cao J, Cary BP, Belousoff MJ, Wootten DL
Sample: CGRP Receptor in complex with dC2_049
Fitted models: 9mm5
Deposition Authors: Cao J, Cary BP, Belousoff MJ, Wootten DL
De novo design of miniproteins targeting GPCRs.
Muratspahic E,
Feldman D,
Kim DE,
Qu X,
Bratovianu AM,
Rivera-Sanchez P,
Voss JH,
Hertz EPT,
Jeppesen M,
Dimitri F,
Sakamoto K,
Nallathambi A,
Peceli P,
Cao J,
Cary BP,
Belousoff MJ,
Keov P,
Trinh PNH,
Chen Q,
Ren Y,
Fine J,
Mishra S,
Dalal A,
Sinha S,
Banerjee R,
Ganguly M,
Karuppusamy KV,
Sappington I,
Schlichthaerle T,
Zhang JZ,
Pillai A,
Coventry B,
Mihaljevic L,
Bauer MS,
Torres SV,
Motmaen A,
Lee GR,
Tran L,
Wang X,
Goreshnik I,
Vafeados DK,
Svendsen JE,
Hosseinzadeh P,
Lindegaard N,
Brandt M,
Waltenspuhl Y,
Deibler K,
Deweid L,
Bennett A,
Schoppe J,
Dong T,
Yan X,
Oostdyk L,
Cao W,
Anantharaman L,
Weisser JJ,
Bastlund JF,
Bundgaard C,
Asuni AA,
English JG,
Stewart LJ,
Halloran L,
Spangler JB,
Lieber A,
Shukla AK,
Sexton PM,
Roth BL,
Krumm BE,
Wootten D,
Tate CG,
Norn C,
Baker D
(2026) Nature
(2026) Nature
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): 1150083 (Australia)
- Australian Research Council (ARC): DP210101504 (Australia)
- National Health and Medical Research Council (NHMRC, Australia): 2026300 (Australia)
- Australian Research Council (ARC): IC200100052 (Australia)
