EMD-73370

Single-particle
2.9 Å
EMD-73370 Deposition: 16/10/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73370

Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 (E191A) in complex with T20P14-B complex, protomer A focused refinement

EMD-73370

Single-particle
2.9 Å
EMD-73370 Deposition: 16/10/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Complex of SARS-CoV-2 nsp10-nsp14 E191A mutant with a synthetic T20P14-B and P6 RNA
Fitted models: 9yrl

Deposition Authors: Yang Y, Liu C, Liu B
Mechanism of SARS-CoV-2 resistance to nucleotide analog-based antivirals.
Liu C, Li Y, Cao X, Gleason RJ, Liu B, Yang Y
(2026) Nat Commun
PUBMED: 41530153
DOI: doi:10.1038/s41467-026-68304-8
ISSN: 2041-1723