EMD-49555

Single-particle
3.9 Å
EMD-49555
3D View Gallery
Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49555
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nmt summary report (pdf.gz) Map and 9nmt FULL report (pdf.gz)
EMICSS annotations (xml)

ML418 bound inwardly rectifying potassium channel Kir7.1 R162Q mutant

EMD-49555

Single-particle
3.9 Å
EMD-49555
3D View Gallery
Deposition: 04/03/2025
Map released: 28/01/2026
Last modified: 28/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: tetrameric assembly of identical subunits of the inwardly rectifying potassium channel Kir7.1
Fitted models: 9nmt

Deposition Authors: Peisley A, Su M, Cone R

ML418 Binds in the Pore of the Inward Rectifier Kir7.1 and Inhibits the Channel In Vivo to Reduce Food Intake and Body Weight
Peisley A, Su M, Cone R
To Be Published
Grant Support: