EMD-70557

Helical reconstruction
2.92 Å
EMD-70557
3D View Gallery
Deposition: 09/05/2025
Map released: 24/12/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-70557

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9oka summary report (pdf.gz) Map-9oka FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cardiac lambda-6 light chain amyloid AL-224L single protofilament

EMD-70557

Helical reconstruction
2.92 Å
EMD-70557
3D View Gallery
Deposition: 09/05/2025
Map released: 24/12/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cardiac tissue-derived immunoglobulin l6 light chain AL-224L
Fitted models: 9oka

Deposition Authors: Hicks CW, Gursky O, Huda N
Cryo-EM of Cardiac AL-224L Amyloid Reveals Shared Structural Motifs and Mutation-induced Differences in lambda 6 Light Chain Fibrils.
Hicks CW, Prokaeva T, Spencer B, Jayaraman S, Huda N, Wong S, Chen H, Sanchorawala V, Lavatelli F, Gursky O
(2025) J Mol Biol , 438 , 169591 - 169591
PUBMED: 41389958
DOI: doi:10.1016/j.jmb.2025.169591
ISSN: 1089-8638
ASTM: JMOBAK