EMD-71588
Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and FAB ATX-42-2 closed conformation
EMD-71588
Single-particle11.6 Å
Deposition: 03/07/2025Map released: 24/12/2025
Last modified: 08/07/2026
Sample Organism:
human gammaherpesvirus 4,
Mus musculus
Sample: coexpress glycoprotein gh/gL complex 1:1 with glycoprotein gp42, then complex 1:1 with FAB ATX-42-2
Deposition Authors: Lang K
,
Kher G ,
Chan CB ,
Pancera M
Sample: coexpress glycoprotein gh/gL complex 1:1 with glycoprotein gp42, then complex 1:1 with FAB ATX-42-2
Deposition Authors: Lang K
,
Kher G ,
Chan CB ,
Pancera M
Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development.
Chhan CB,
Lang K ,
Davis AR ,
Wan YH ,
Aldridge NT ,
Kher G ,
Scharffenberger SC ,
Hardy SR ,
Iureniev R ,
Giltiay NV ,
Edwards KR ,
Radtke S ,
Kiem HP ,
Pancera M ,
McGuire AT
(2026) Cell Rep Med , 7 , 102618 - 102618
,
Davis AR ,
Wan YH ,
Aldridge NT ,
Kher G ,
Scharffenberger SC ,
Hardy SR ,
Iureniev R ,
Giltiay NV ,
Edwards KR ,
Radtke S ,
Kiem HP ,
Pancera M ,
McGuire AT
(2026) Cell Rep Med , 7 , 102618 - 102618
Grant Support: