EMD-52312

Single-particle
3.81 Å
EMD-52312
3D View Gallery
Deposition: 11/12/2024
Map released: 24/12/2025
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52312

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hnq summary report (pdf.gz) Map-9hnq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

a5b3 GABAA Receptor bound to GABA and Mb25 in desensitized state in detergent micelles

EMD-52312

Single-particle
3.81 Å
EMD-52312
3D View Gallery
Deposition: 11/12/2024
Map released: 24/12/2025
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Escherichia coli
Sample: a5b3 GABAA receptor in resting state bound to zinc and butyrate
Fitted models: 9hnq

Deposition Authors: Cowgill J , Fan C , Howard RJ , Lindahl E
Structural basis for activation and potentiation in a human alpha 5 beta 3 GABA A receptor.
Cowgill J , Fan C , Steyaert J , Howard RJ , Lindahl E
(2026) Nat Commun , 17
PUBMED: 42297817
DOI: doi:10.1038/s41467-026-74279-3
ISSN: 2041-1723