EMD-71586
Negative stain EM map of EBV glycoprotein gH/gL in complex with glycoprotein gp42 and FAB ATX-42-2 Open conformation
EMD-71586
Single-particle8.45 Å
Deposition: 03/07/2025Map released: 24/12/2025
Last modified: 08/07/2026
Sample Organism:
human gammaherpesvirus 4,
Mus musculus
Sample: Coexpressed EBV surface glycoprotein gH/gL complex 1:1 with glucoprotein gp42 and then 1:1 with FAB ATX-42-2
Deposition Authors: Lang K
,
Kher G ,
Chan CB ,
Pancera M
Sample: Coexpressed EBV surface glycoprotein gH/gL complex 1:1 with glucoprotein gp42 and then 1:1 with FAB ATX-42-2
Deposition Authors: Lang K
,
Kher G ,
Chan CB ,
Pancera M
Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development.
Chhan CB,
Lang K ,
Davis AR,
Wan YH,
Aldridge NT,
Kher G ,
Scharffenberger SC,
Hardy SR,
Iureniev R,
Giltiay NV,
Edwards KR,
Radtke S,
Kiem HP,
Pancera M ,
McGuire AT
(2026) Cell Rep Med , 7 , 102618 - 102618
,
Davis AR,
Wan YH,
Aldridge NT,
Kher G ,
Scharffenberger SC,
Hardy SR,
Iureniev R,
Giltiay NV,
Edwards KR,
Radtke S,
Kiem HP,
Pancera M ,
McGuire AT
(2026) Cell Rep Med , 7 , 102618 - 102618
Grant Support: