Cryo-EM structure of a designed pyridoxal phosphate (PLP) synthase fused to a designed circumsporozoite protein antigen from Plasmodium falciparum (CSP-P1-CSP and CSP-P2-CSP)

Constituent EM map: Focused refinement on Ry34 of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

Constituent EM map: Focused refinement on BSol of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on JSol+CSol of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on Ry34 of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on BSol of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

Constituent EM map: Focused refinement on NTD+SPRY+Calstabin-1 of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on Ry34 of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on NTD+SPRY+Calstabin-1 of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

Constituent EM map: Focused refinement on Ry12 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on Ry34 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on Ry12 of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

Constituent EM map: Focused refinement on Ry12 of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on JSol+CSol of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on NTD+SPRY+Calstabin-1 of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on JSol+CSol of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on JSol+CSol of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

Constituent EM map: Focused refinement on Ry12 of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on BSol of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on NTD+SPRY+Calstabin-1 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on BSol of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)

Constituent EM map: Focused refinement on Ry34 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on Ry12 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on BSol of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on NTD+SPRY+Calstabin-1 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)

Constituent EM map: Focused refinement on JSol+CSol of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)

Cryo-EM structure of G6PT1 in complex with Glucose-6-phosphate

Cryo-EM structure of SARS-CoV-2 spike S2' trimer

Cryo-EM structure of SARS-CoV-2 spike S2' trimer (local map 1)

Cryo-EM Structure of Human GPR158 Bound to Nanobody Nb20

Cryo-EM structure of G6PT1 in complex with Chlorogenic acid

Cryo-EM structure of violaxanthin-chlorophyll-a-binding protein with red shifted Chl a (rVCP) from Trachydiscus minutus at 2.4 angstrom

Cryo-EM structure of the Lhcp trimer from Ostreococcus tauri at 1.94 angstrom resolution

Cryo-EM structure of SARS-CoV-2 spike S2' trimer (local map 2)

Cryo-EM structure of SARS-CoV-2 spike S2' trimer (dimer of trimer)

Cryo-EM structure of lumen facing G6PT1 in the apo state

Cryo-EM structure of G6PT1 in complex with phosphate ion

Type III-B CRISPR-Cas effector from Archaeoglobus fulgidus (Form 1)

Cryo-EM analysis of TLR7 in complex with mGrUrC

FADD-DED filaments coordinate complex IIa assembly during TNF-induced apoptosis

Type III-B CRISPR-Cas effector from Archaeoglobus fulgidus (Form 2)

Cryo-EM structure of hAQP11 in LMNG

Cerebellar GluA1/4 LBD tetramer (focused refinement)

cryo-EM structure of RNF20/RNF40-RAD6A-Ub in complex with H2BS112GlcNAc nucleosome

HSV Helicase-primase complex bound to IM-250

HSV Helicase-primase complex bound to amenamevir

HSV helicase-primase complex bound to pritelivir

Yersinia entomophaga holotoxin complex in prepore conformation

Yersinia entomophaga holotoxin complex in pore conformation

Yersinia entomophaga toxin complex TcA subunit

HSV replication fork complex bound to pritelivir

Local refinement of HSV UL30 in HSV replication fork complex

Local refinement of HSV UL5 in IM-250 bound H/P complex

Low resolution map of HSV replication fork complex

Local refinement of interface of HSV UL5 and UL30 in the replication fork

Local refinement of HSV UL5 in HSV replication fork complex

Local refinement of HSV UL5 in amenamevir-bound H/P complex

Local refinment of HSV UL5 in pritelivir-bound H/P complex

Local refinement of HSV UL8 in pritelivir-bound H/P complex

Local refinement of HSV UL8 in amenamevir-bound H/P complex

HIV-1 R18L CA hexamer

HIV-1 R18L CA pentamer from capsid-like particles assembled in 1 M NaCl

Cryo-EM structure of EBV gB prefusion construct C3-GT

AcA-EI-shaker Class B

Ravn marburgvirus glycoprotein

Focused map of COP9 signalosome deneddylation state with cullin-4A

AcA-EI-shaker Class A

RAVV glycoprotein in complex with hNPC1-C

Potassium voltage-gated channel GT-Shaker Class B

Potassium voltage-gated channel GT-Shaker Class C

GT-Shaker TM domain in C4 symmetry

GT-Shaker T1 domain in C4 symmetry

Cryo-EM structure of post-fusion EBV gB in complex with AMMO2 fab

Hsp70-NBD:Bag1:Rpn1 ternary complex class 2

Co-chaperone Bag1-bound human 26S proteasome in SBAG3 state

Hsp70-NBD:Bag1:Rpn1 ternary complex class 1

Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state

Co-chaperone Bag1-bound human 26S proteasome in SBAG1 state

Cryo-EM structure of Croatia 2023 H3N2 Influenza A hemagglutinin (HA) trimer

RAVV GP in complex with Nanosota-MB1

CryoEM structure of filament of Bacillus subtilis TIR domain protein SpbK

CryoEM structure of the YonE portal protein from Bacillus phage SPbeta

Cryo-EM structure of human DNMT3A/3L

Ovorubin from the golden apple snail (Pomacea canaliculata)

Structure of GPCR megacomplex bound to agonists

The PSI3-IsiA43 complex with a closed double ring of IsiA proteins bound to a trimeric PSI core

Structure of GPR119-Gs complex bound to AR231453

Structure of beta1-AR-Gs complex bound to epinephrine and an allosteric modulator

The PSI1-IsiA13 complex with double-layered IsiA proteins bound to the monomeric PSI core

Cryo-EM structure of ASFV DNA polymerase in a DNA replication state

Croy-EM structure of HEV_4 p495 virus-like particle in complex with antibody 6H8

Structure of GPR119-Gs complex bound to an allosteric modulator

Cryo-EM structure of the cytosolic ARMH2-EFCAB9-CATSPERz subcomplex of the mouse CatSpermasome

Gi-bound kappa opioid receptor in complex with dynorphin and positive allosteric modulator MPAM-15

The apo structure (State 1) of African Swine Fever Virus DNA polymerase

Hexamer Msp1 from S.cerevisiae(with a catalytic dead mutation) in complex with an unknown peptide substrate

The local cryo-EM map of CATSPEREpsilon of Monomer A of the CatSper dimer

The local cryo-EM map of CATSPEREpsilon of Monomer B of the CatSper dimer

The local cryo-EM map of the gamma-gamma interface of the CatSper trimer

The local cryo-EM map of CATSPERBeta of Monomer A of the CatSper dimer

The local cryo-EM map of CATSPERGamma of Monomer B of the CatSper dimer

The local cryo-EM map of the extracellular region of the Monomers B and A' of the CatSper trimer

The local cryo-EM map of CATSPERGamma of Monomer A of the CatSper dimer

The local cryo-EM map of CATSPERBeta of Monomer B of the CatSper dimer

The overall cryo-EM map of the mouse CatSper dimer

The local cryo-EM map of CATSPERDelta of Monomer A of the CatSper dimer

Cryo-EM structure of RSV pre-F in complex with antibody CNR2042

Cryo-EM structure of RSV pre-F in complex with antibody CNR2053

The local cryo-EM map of the eta-eta interface of the CatSper dimer

The local cryo-EM map of the extracellular region of Monomer A of the CatSper trimer

The local cryo-EM map of the transmembrane region of the CatSper dimer

The local cryo-EM map of CATSPERDelta of Monomer B of the CatSper dimer

Cryo-EM structure of E. coli glycine decarboxylase (P-protein) apo

The overall cryo-EM map of the mouse CatSper trimer

Cryo-EM structure of RSV pre-F in complex with antibody CNR2056

Cryo-EM structure of RSV pre-F in complex with antibody CNR2047

SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class A

SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class C

Cryo-EM structure of hnRAC1-2,8beta fibril polymorph1

Cryo-EM structure of hnRAC1-2,8beta fibril polymorph2

Cryo-EM structure of RSV pre-F trimer in complex with CNR2056/CNR2047

Cryo-EM structure of hnRAC1-2,8homobeta fibril

SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class B

SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class D

Cryo-EM structure of RSV pre-F monomer in complex with CNR2056/CNR2047

Cryo-EM structure of RSV pre-F dimer in complex with CNR2056/CNR2047

Cryo-EM structure of hMPV pre-F in complex with antibody CNR2047

SuperFi Cas9 - 22nt sgRNA - DNA ternary complex

SuperFi Cas9 - 20nt sgRNA - DNA ternary complex Class E

SuperFi Cas9 - 22nt sgRNA - DNA ternary complex Class B

SuperFi Cas9 - 22nt sgRNA - DNA ternary complex Class C

cryoEM structure of retron-Eco7 complex

CryoEM structure of Western equine encephalitis virus California VLP in complex with VLDLR-LA3

GTPBP1*GDP*Phe-tRNA*ribosome in the post-GTP hydrolysis state, Structure IV

GTPBP1*GCP*Phe-tRNA*ribosome in the GTPase activation-like state, Structure III