EMD-72781

Single-particle
2.9 Å
EMD-72781
3D View Gallery
Deposition: 19/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72781

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ycp summary report (pdf.gz) Map-9ycp FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

HSV Helicase-primase complex bound to IM-250

EMD-72781

Single-particle
2.9 Å
EMD-72781
3D View Gallery
Deposition: 19/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human alphaherpesvirus 1 strain R-15
Sample: HSV Helicase-primase complex with IM-250
Fitted models: 9ycp

Deposition Authors: Yu Z, Abarham J
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly.
Yu Z, Sathyanarayana P, Liu C, Tan JMJ, Yang P, Das B, Hu S, Fan X, Ji C, Weller SK, Shekhar M, Coen DM, Kranzusch PJ, Loparo JJ, Abraham J
(2026) Cell , 189 , 478 - 494.e18
PUBMED: 41468884
DOI: doi:10.1016/j.cell.2025.11.041
ISSN: 1097-4172
Grant Support: