EMD-72789

Single-particle
2.8 Å
EMD-72789
3D View Gallery
Deposition: 19/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72789

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ycv summary report (pdf.gz) Map-9ycv FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

HSV Helicase-primase complex bound to amenamevir

EMD-72789

Single-particle
2.8 Å
EMD-72789
3D View Gallery
Deposition: 19/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human alphaherpesvirus 1 strain R-15
Sample: HSV helicase-primase complex bound to amenamevir
Fitted models: 9ycv

Deposition Authors: Yu Z, Abraham J
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly.
Yu Z, Sathyanarayana P, Liu C, Tan JMJ, Yang P, Das B, Hu S, Fan X, Ji C, Weller SK, Shekhar M, Coen DM, Kranzusch PJ, Loparo JJ, Abraham J
(2026) Cell , 189 , 478 - 494.e18
PUBMED: 41468884
DOI: doi:10.1016/j.cell.2025.11.041
ISSN: 1097-4172
Grant Support: