EMD-72764

Single-particle
3.8 Å
EMD-72764
3D View Gallery
Deposition: 18/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72764

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9yc9 summary report (pdf.gz) Map-9yc9 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HSV replication fork complex bound to pritelivir

EMD-72764

Single-particle
3.8 Å
EMD-72764
3D View Gallery
Deposition: 18/09/2025
Map released: 31/12/2025
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human alphaherpesvirus 1 strain R-15
Sample: HSV replisome bound to fork DNA
Fitted models: 9yc9

Deposition Authors: Yu Z, Abraham J
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly.
Yu Z, Sathyanarayana P, Liu C, Tan JMJ, Yang P, Das B, Hu S, Fan X, Ji C, Weller SK, Shekhar M, Coen DM, Kranzusch PJ, Loparo JJ, Abraham J
(2026) Cell , 189 , 478 - 494.e18
PUBMED: 41468884
DOI: doi:10.1016/j.cell.2025.11.041
ISSN: 1097-4172
Grant Support: