EMD-65225

Single-particle
3.47 Å
EMD-65225
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Deposition: 02/07/2025
Map released: 31/12/2025
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-65225
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9vor summary report (pdf.gz) Map and 9vor FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of Human GPR158 Bound to Nanobody Nb20

EMD-65225

Single-particle
3.47 Å
EMD-65225
3D View Gallery
Deposition: 02/07/2025
Map released: 31/12/2025
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: GPR158 complexed with Nb20
Fitted models: 9vor

Deposition Authors: Laboute T , Zucca S , Sial M, Sharma M , Brunori G, Singh S , Singh A, Martemyanov K
Targeting mGlyR with nanobodies for depression.
Laboute T , Zucca S , Sial OK, Sharma M , Brunori G, Singh S , Nageswar KV, Peng H , Rader C , Becker JA , Le Merrer J , Singh AK , Martemyanov KA
(2026) Nat Commun , 17 , 831 - 831
PUBMED: 41588006
DOI: doi:10.1038/s41467-026-68339-x
ISSN: 2041-1723