EMD-71814

Single-particle
3.66 Å
EMD-71814
3D View Gallery
Deposition: 24/07/2025
Map released: 31/12/2025
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71814

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9prw summary report (pdf.gz) Map-9prw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human DNMT3A/3L

EMD-71814

Single-particle
3.66 Å
EMD-71814
3D View Gallery
Deposition: 24/07/2025
Map released: 31/12/2025
Last modified: 06/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: DNMT3A/3L
Fitted models: 9prw

Deposition Authors: Lu J, Song J
Structural insight into hierarchical DNMT3A autoinhibition and its dysregulation in disease.
Lu J, Vig E, Chen J, Gretarsson KH, Khudaverdyan N, Shao Z, Lu C, Chang CA, Song J
(2026) Nat Commun , 17
PUBMED: 41708613
DOI: doi:10.1038/s41467-026-69563-1
ISSN: 2041-1723