Cryo-EM structure of the Arabidopsis thaliana C2S2M2-type PSII supercomplex focused map part C

Cryo-EM structure of the Arabidopsis thaliana C2S2M2-type PSII supercomplex focused map part A

Cryo-EM structure of the Arabidopsis thaliana C2S2M2-type PSII supercomplex focused map part B

C-terminal focused EM map of STOM-single reconstructed with C8 symmetry

Overall structure of STOM-double reconstructed with C16 symmetry.

Cryo-EM structure of the Arabidopsis thaliana C4S4M4-type PSII supercomplex focused map part A

complex of anti-CRISPR Protein

C-terminal focused EM map of STOM-liposome reconstructed with C8 symmetry

Cryo-EM structure of STOM complex reconstitution into liposomes

anti-Crispr protein in apo form

CryoEM structure of EV-D68 US/MO/14-18947 in complex with MFSD6-L3

Cryo-EM structure of TtCoAT-ADLP complex in ligand-free form

CryoEM structure of EV-D68 US/KY/14-18953 in complex with MFSD6-L3

CryoEM structure of EV-D68 US/KY/14-18953 mature virion

Cryo-EM structure of TtCoAT-ADLP complex in NAD+-bound form

CryoEM structure of EV-D68 US/MO/14-18947 mature virion

Local refinement cryo-EM map of CXXC-NCP component of the mutant MHKKKQ DNMT1-umNCP complex

Composite cryo-EM density map of DNMT1 in complex with unmethylated nucleosome core particle

Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (Composite map from PHENIX)

The cryo-EM structure of the mutant MHKKKQ DNMT1-umNCP complex

Structure of human TM6SF1

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)

Local refinement cryo-EM map of DNMT1 C-terminal domains in complex with unmethylated nucleosome core particle

Local refinement cryo-EM map of DNMT1 CXXC domain in complex with unmethylated nucleosome core particle

Cryo-EM consensus map of the DNMT1 in complex with unmethylated nucleosome core particle

Structure of cholesterol binding deficient human TM6SF1

Cryo-EM consensus map of the mutant MHKKKQ DNMT1-umNCP complex

Local refinement cryo-EM map of mutant MHKKKQ DNMT1 component of the mutant MHKKKQ DNMT1-umNCP complex

Cryo-EM consensus map of the mutant MHKKKQ DNMT1-umNCP complex showing the density of the RFTS domain

Cryo-EM of filamentous alkaline phosphatase

Apo EcHerA Hexamer Assembly

Apo EcHerA Pentamer Assembly

Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649

human polycystin-2 with clinical variant D511V

Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649, class 2

Apo EcHerA Tetramer Assembly

Cryo-EM of (D, D)-2NapFF tube

Gammacoronavirus IBV apo-nsp15

Gammacoronavirus IBV dsRNA-bound nsp15

1D6 Fab/NA25:Ab complex

Cryo-EM structure of a novel beta-galactosidase (EiGH116) from animal gut

Cryo-EM structure of a novel beta-galactosidase (HhGH116) from human gut

Cryo-EM structrue of kpNLRL filament

Complex of FMDV O/18074 and porcine-derived neutralizing monoclonal antibody pO18-29

Complex of FMDV O/HN/CHA/93 and porcine-derived neutralizing monoclonal antibody pO18-29

Human sperm nuclear 20S proteasome

Human sperm 26S proteasome complex isolated from native source

HRV E1007A mutant

Human sperm 20S-AAA-ATPase proteasome complex isolated from native source

PA200-20S-PA200 complex

HRV virion E2250A mutant

Human sperm 20S proteasome complex isolated from native source

Human sperm 20S-PA200 proteasome complex isolated from native source

Human sperm nuclear proteasome PA200-20S

cryo-EM structure of wild-type MscL from Escherichia coli in MSP nanodisc

cryo-EM structure of MscL G22S mutant from Escherichia coli in MSP nanodisc

Focused subtomogram average of the transition zone linker (linker1) in human airway cilia

In situ subtomogram average of the transition zone linker in human airway cilia (composite map)

Focused subtomogram average of the transition zone linker (linker4) in human airway cilia

Focused subtomogram average of the transition zone doublet microtubule (d) in human airway cilia

Focused subtomogram average of the transition zone doublet microtubule (c) in human airway cilia

Focused subtomogram average of the transition zone doublet microtubule (b) in human airway cilia

Cryo-EM Structure of GTP Cyclohydrolase I from Candida albicans bound to 7-Deaza GTP and BH2 at 1.96 A

Focused subtomogram average of the transition zone linker (linker3) in human airway cilia

In situ subtomogram average of the transition zone linker in human airway cilia (consensus map)

Focused subtomogram average of the transition zone doublet microtubule (a) in human airway cilia

Focused subtomogram average of the transition zone doublet microtubule (e) in human airway cilia

Focused subtomogram average of the transition zone linker (linker2) in human airway cilia

RNA polymerase ribozyme 85h34 replication complex, consensus structure.

In situ subtomogram average of the transition zone doublet microtubule in human airway cilia (consensus map)

RNA polymerase ribozyme 85h34 replication complex, subclass 2 structure.

In situ subtomogram average of the transition zone doublet microtubule in human airway cilia (composite map)

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)

Cryo-EM structure of a bovine CLC-K S68N/R355K chloride channel with inhibitor M-BIM1

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)

Composite map of BCDX2-CX3-RAD51 complex

Cryo-EM structure of a bovine CLC-K S68N/R355K chloride channel

Cryo-EM structure of a bovine CLC-K S68N/R355K chloride channel with inhibitor M-BIM15

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened WalkerB1 local refinement map from cryoSPARC)

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR ( Consensus map from cryoSPARC)

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)

Cryo-EM structure of a bovine CLC-K S68N/R355K chloride channel with 100 mM Ca2+

V-shaped (channel-formed), ATP-bound, VX809-bound conformation of wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)

Local refinement of CX3 body of BCDX2-CX3-RAD51 complex

Composite map of DX2-CX3 bound to RAD51 filament

Local refinement of RAD51-RAD51 body of BCDX2-CX3-RAD51 complex

Local refinement of BCDX2 body of BCDX2-CX3-RAD51 complex

Local refinement of XRCC3-RAD51-RAD51 body of DX2-CX3 bound to RAD51 filament

Local refinement of RAD51 filament body of DX2-CX3 bound to RAD51 filament

Cryo-EM structure of apo full-length mouse TRPML2 channel in lipid nanodisc, closed II

Cryo-EM structure of designed Orb2 amyloid (LVLVF, polymorph 4)

Local refinement of CDX2 body of DX2-CX3-RAD51 filament, unsharpened map

Cryo-EM structure of apo full-length mouse TRPML2 channel in lipid nanodisc, closed III

Bacteroides thetaiotaomicron CcsBA mutant W703C

human ORAI1 in C6 symmetry

human ORAI1 in C2 symmetry

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation D

Overall map of mGlu7-beta-arrestin 1 complex

Cytochrome bc1 complex from Rhodobacter capsulatus at 2.16 A resolution

R. capsulatus cytochrome bc1 dimer with one Rieske protein in the c position and one in an intermediate position

Focused map of mGlu7 ECDs in mGlu7-beta-arrestin 1 complex

Overall map of mGlu5-beta-arrestin 1 complex

Cryo-EM structure of ESG-2-37-bound D3 dopamine receptor with mini-Go

Cryo-EM structure of the mGlu5-beta-arrestin 1 complex

Cryo-EM structure of EA-RK-110-bound D3 dopamine receptor

Cryo-EM structure of the mGlu7-beta-arrestin 1 complex

R. capsulatus cytochrome bc1 dimer with both Rieske proteins in the b position

R. capsulatus cytochrome bc1 dimer with both Rieske proteins in the c position

Focused map of mGlu5 VFTs in mGlu5-beta-arrestin 1 complex

Focused map of mGlu5 CRD-TMDs in mGlu5-beta-arrestin 1 complex

Focused map of beta-arrestin 1 in mGlu5-beta-arrestin 1 complex

R. capsulatus cytochrome bc1 dimer with one Rieske protein in the c position and one in the b position

Rhodobacter capsulatus +2Ala insertion mutant of cytochrome bc1 dimer at 2.41 A

Cryo-EM structure of EA-Ri-112-bound D3 dopamine receptor with mini-Go

Focused map of mGlu7 TMDs-beta-arrestin 1 in mGlu7-beta-arrestin 1 complex

Cryo-EM structure of the 2:1 mGlu7-ELFN1 complex

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation C

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation B

Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation A

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

The spike protein of HCoV-OC43 obtained from data collected on 300 kV Krios with Gatan K3 detector

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

CryoEM Structure of human MDA5 with dsRNA (one protein subunit on dsRNA)

Cryo-EM structure of designed Orb2 amyloid (FIMMF, polymorph 2)

Cryo EM structure of a peroxidoxin from Trypanosoma brucei (reduced form)

Gammacoronavirus dual dsRNA-bound IBV nsp15 (same trimer)

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

The spike protein of HCoV-OC43 obtained from data collected on 100 kV Tundra with Ceta detector

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

CryoEM Structure of human MDA5 in complex with dsRNA (two protein subunits on dsRNA)

Gammacoronavirus dual dsRNA-bound IBV nsp15 (opposite trimers)

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Arabidopsis thaliana V-type ATPase, State 1

Arabidopsis thaliana V-type ATPase, State 2, Backbone model

Arabidopsis thaliana V-type ATPase, State 3, Backbone model

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Cryo EM structure of a formate acetyltransferase (PFL) from Amygdalobacter nucleatus

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Cryo EM structure of GTP cyclohydrolase 1 (FolE) from Mycobacterium tuberculosis in complex with 8-oxo GTP

Arabidopsis thaliana V-type ATPase, State 1 bound to OXR5, Backbone model

Structural insights into the exosite-mediated activation of Factor IX by Factor XIa using cryoEM

Cryo EM structure of a formate acetyltransferase (PFL) from Fannyhessea vaginae

Porcine ATP synthase with inhibitory protein IF1, F1 domain, E-state

Cryo-EM of chaperon usher pathway pilus from Stenotrophomonas maltophilia

Cryo-EM structure of the T641E mutant of the outwardly rectifying potassium channel TOK1 from Saccharomyces cerevisiae

The mouse nucleosome structure containing H3mm15

Cryo-EM structure of the outwardly rectifying potassium channel TOK1 from Saccharomyces cerevisiae in a GDN micelle

cryo-em structure of tri-hexameric hLRRC8A double mutation

Cryo-EM structure of homo-hexameric hLRRC8A double mutation W168L/L402W

Cryo-EM structure of nomo-hexameric hLRRC8A L402W with ATP

Cryo-EM structure of homo-hexameric hLRRC8A L402W

Cryo-EM structure of homo-hexameric hLRRC8A double mutation I2C/L402W

Human GGPPS Bound to Selective Inhibitor CML-07-119 in theExposed Binding Site Conformation

Two AIP1 bound to the Barbed End of cofilin actin

Human GGPPS Bound to Selective Inhibitor CML-07-119 in theShielded Binding Site Conformation

Human GGPPS in the Closed Hexamer Conformation

Cofilactin filament

Cryo-EM Structure of Human GGPPS Bound to Selective Inhibitor CML-07-119

Cofilactin filament with one AIP1 bound to middle of the filament

Cofilactin filament with two AIP1 bound to middle of the filament

Human GGPPS in the Open Hexamer Conformation

Pointed end of cofilin bound F-actin

Two AIP1 bound to same side of cofilin filament (stacked AIP1)

One AIP1 bound to the Barbed End of cofilin actin

Structure of complement C3 in an extended conformation

Prefusion-stabilized Nipah virus fusion protein in complex with inhibitory nanobody F112

Prefusion-stabilized Hendra virus fusion protein in complex with inhibitory nanobody F123

Cryo-EM structure of the NLRP3 decamer bound to the inhibitor BAL-1516

cryo-EM structure of LwHicAB-crRNA

Cryo-EM structure of ESG-2-36-bound D3 dopamine receptor with mini-Go

Cryo-EM structure of Free fatty acid receptor 2 (FFA2)-ARK1 with GLPG0974

Cryo-EM structure of Arthrobacter psychrolactophilus Trehalose synthase

Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with CS-42 Fab (local refinement of RBD and Fv)

Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with SR-23 Fab (local refinement of RBD and Fv)

Cryo-electron tomography of AF647-gold-conjugated W27 binding to E.Coli membrane blebs.

Cryo-EM structure of zika virus complexed with Fab 1C11

LINC complex from human sperm

Calyx from human sperm

5HT2AR-miniGq heterotrimer in complex with a psychedelic psilocin

IR of NPC from human sperm

LR of NPC from human sperm

5HT2AR-miniGq heterotrimer in complex with a selective agonist IHCH-2330

5HT2BR-fab heterotrimer in complex with a novel antagonist IHCH-2330

Cryo-EM structure of Ceg14-AnkJ-Actin complex

Cryo-EM structure of Ceg14 and AnkJ

CryoEM structure of hGZMA-hGSDMB

Cryo-EM structure of Ceg14 and Actin complex

CryoEM structure of hGZMA-hGSDMBctd

The cryo-EM map of GPI-MT-I complex with Gpi14 D38A mutation

The cryo-EM map of GPI-MT-I complex

Rad55-Rad57-SHU-Rad51

Structure of AlphaIIbBeta3-R21C11 Fab in the near-bent conformation

Septin tetrameric complex from Caenorhabditis elegans by Cryo-EM

KN1dep depolymerase with C1 symmetry against KN1 serotype Klebsiella pneumoniae,(KN1dep-C1)

Tetrameric cystathionine beta-synthase of Mycobacterium tuberculosis bound to O-Benzylhydroxylamine

Tetrameric cystathionine beta-synthase of Mycobacterium tuberculosis bound to AOAA

rod 1 local map of phycobilisome from extremophilic red alga

Cryo-EM structure of Dp42 depolymerase with C1 symmetry against KN1 serotype Klebsiella pneumoniae,(Dp42-C1)

rod 2 local map of phycobilisome from extremophilic red alga

Cryo-EM structure of Dp42 depolymerase with C3 symmetry against KN1 serotype Klebsiella pneumoniae,(Dp42-C3)

structure of human propionyl-coenzyme A carboxylase in BC binding state

Cryo-EM structure of STOM-double complex purified using DDM

Cryo-EM structure of the Arabidopsis thaliana C4S4M4-type PSII supercomplex focused map part B

Overall structure of STOM-single reconstructed with C16 symmetry.

Overall structure of STOM-liposome reconstructed with C16 symmetry.

Cryo-EM structure of STOM-single complex purified using DDM

Cryo-EM structure of the Arabidopsis thaliana C4S4M4-type PSII supercomplex focused map part C

C-terminal focused EM map of STOM-double reconstructed with C8 symmetry

Cryo-EM structure of the Arabidopsis thaliana C4S4M4-type PSII supercomplex focused map part D

Cryo-EM structure of DONepi, a deoxynivalenol 3-epimerase from Nocardioides sp. S5-5