EMD-49153

Single-particle
2.76 Å
EMD-49153
3D View Gallery
Deposition: 10/02/2025
Map released: 09/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49153

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n8y summary report (pdf.gz) Map-9n8y FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649

EMD-49153

Single-particle
2.76 Å
EMD-49153
3D View Gallery
Deposition: 10/02/2025
Map released: 09/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Metabotropic Glutamate Receptor 8 dimer
Fitted models: 9n8y

Deposition Authors: Marx DC, Levitz JT
Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins.
Marx DC, Huynh K, Gonzalez-Hernandez AJ , Strauss A , Rico C, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J , Eliezer D , Khelashvili G , Levitz J
(2026) Nat Commun , 17
PUBMED: 42722693
DOI: doi:10.1038/s41467-026-77556-3
ISSN: 2041-1723