EMD-55481

Single-particle
4.18 Å
EMD-55481
3D View Gallery
Deposition: 24/10/2025
Map released: 09/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55481

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

cryo-em structure of tri-hexameric hLRRC8A double mutation

EMD-55481

Single-particle
4.18 Å
EMD-55481
3D View Gallery
Deposition: 24/10/2025
Map released: 09/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: cryo-em structure of tri-hexameric hLRRC8A double mutation

Deposition Authors: Bertelli S , Wang L , Klussendorf M , Pusch M , Dutzler R , Stauber T
The intracellular subdomain of the volume-regulated anion channel subunit LRRC8A is a hotspot of channel activation.
Bertelli S , Wang L , Klussendorf M , Gavazzo P, Pusch M , Dutzler R , Stauber T
(2026) Nat Commun , 17
PUBMED: 42754616
DOI: doi:10.1038/s41467-026-77507-y
ISSN: 2041-1723
Grant Support: