EMD-48749

Single-particle
3.93 Å
EMD-48749
3D View Gallery
Deposition: 22/01/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48749

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mys summary report (pdf.gz) Map-9mys FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

The cryo-EM structure of the mutant MHKKKQ DNMT1-umNCP complex

EMD-48749

Single-particle
3.93 Å
EMD-48749
3D View Gallery
Deposition: 22/01/2025
Map released: 09/09/2026
Last modified: 09/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Xenopus laevis, Homo sapiens, Escherichia coli
Sample: mutant MHKKKQ DNMT1-umNCP complex
Fitted models: 9mys

Deposition Authors: Fang J , Song J

The DNMT1 CXXC domain senses CpG islands for DNA methylation inhibition
Fang J , Song J
(2026) To Be Published