Cryo-EM structure of the engineered vector AAV2.ATX002

Structure of 3TM-SAVED dimer bound to 2'3'-cGAMP

Structure of 3TM-SAVED Filament bound to 2'3'-cGAMP

Raw consensus map of Type II-A CRISPR integrase prespacer catching complex, State I

Type II-A CRISPR integrase pre-integration complex

Type I-A CRISPR integrase prespacer catching complex, State II

Type II-A CRISPR integrase complex, apo form

Cryo-EM structure of ATP-bound Oryza sativa MRP5 with E1424Q mutation

Cryo-EM structure of rice multidrug resistance protein 5 (MRP5) with InsP6 in state B

Cryo-EM structure of the human P2X3 receptor in the ATP-bound, desensitized state

PvdL-E2-C3-A3-PCP3 in complex with MLP (NRPS cross-module)

Cryo-EM structure of Oryza sativa multidrug resistance protein 5 (MRP5)

Cryo-EM structure of rice multidrug resistance protein 5 (MRP5) with InsP6 in state A

Cryo-EM structure of the human P2X3 receptor in the ATP- and sivopixant-bound closed state

Cryo-EM structure of a tetrameric XRCC3-RAD51C-RAD51D-XRCC2 complex

70S global refined map of E.coli 70S ribosome complexed with P-site fMet-tRNAfMet and A-site S-beta(2)hydroxyBocK-tRNAPyl

RVFV Gn-Ferritin Nanoparticle

GMPCPP-stabilizsd human alpha1A/beta3 microtubule

GDP human alpha1A/beta3 S239C microtubule

GMPCPP-stabilized human alpha1A/beta3 S239C microtubule

Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 microtubule

Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 S239C microtubule

GDP human alpha1A/beta3 microtubule

Cryo-ET STA of immature HERV-K Gag with the Cc corrector and 60 eV energy filter slit width

Cryo-ET STA of immature HERV-K Gag

CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and energy filter slit width of 20 eV

CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and without an energy filter slit

Cryo-ET STA of immature HERV-K Gag collected with Cc corrector and 20eV energy filter slit width

CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and energy filter slit width of 60 eV

dCas9 bound to off-target 2 EMX1-1 (-)SC DNA minicircle

dCas9 bound to on-target EMX1-1 (-)SC DNA minicircle

in situ S. pombe hibernating ribosome after 7 days of glucose depletion

dCas9 bound to on-target EMX1-1 (-)SC DNA minicircle

dCas9 bound to off-target 1 EMX1-1 (-)SC DNA minicircle

In situ Outer Mitochondrial Membrane Tethered Hibernating Ribosomes from S. pombe under glucose depletion

In situ Free Cytosolic Hibernating Ribosomes from S. pombe under glucose depletion

wtCas9 bound to off-target 1 EMX1-1 (-)SC DNA minicircle

CryoEM structure of mu-opioid receptor - Gi protein complex bound to fluornitrazene (FNZ)

Structure of human CCR4 in apo state

Structure of human CCR4 in complex with PRT193

Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (365) Complex Bound by the MEDI3622 Fab

Structure of human CCR4 in complex with GSK2239633A

Cryo EM Structure of GTP cyclohydrolase 1 (FolE) from Mycobacterium tuberculosis

Structure of human CCR4 in complex with AZD2098

Structure of human CCR4 in complex with FLX475

At S1+2S3 trimer

PSI-LHCE supercomplex from Euglena gracilis.

PSI-LHCE supercomplex from Euglena gracilis

At S3 trimer

Structure of THIK1 complexed with C101248

At 2S1+S3-tRNA trimer

Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl bound

crRNA-guided surveillance (Csy) complex

apo Multidrug resistance-associated protein 2 in complex with AMP-PNP in rest state

Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl and Catch domain resolved

Multidrug resistance-associated protein 2 in complex with MK-571 and ATP

Multidrug resistance-associated protein 2 in complex with MK-571

Cryo-EM structure of Full particle of prokaryotic dsRNA virus phiYY

crRNA-guided surveillance (Csy) complex

Multidrug resistance-associated protein 2 in complex with AMP-PNP in active state

Complex structure of a glycosyltransferase

crRNA-guided surveillance (Csy) complex

Oligomer structure of a glycosyltransferase

Dimer structure of a glycosyltransferase

Cryo-EM map of 9C-BA.4 RBD-S309 Fab complex

Substrate-free human 26S proteasome purified by midnolin, 20S proteasome, RPTs and RPN11 part

Structure of the tip region of the intial complex in bacterial flagellar filament assembly at 3.68 angstroms resolution, conformation 3.

Nav1.5 in complex with quinidine-azo

Cryo-EM structure of cyanobacterial bicarbonate transporter CmpBCD

Cryo-EM structure of GGCX-FX complex

Structure of human 26S proteasome complexed with midnolin(1-111+337-468)

Glycogen phosphorylase tetramer from E. coli

Glycogen phosphorylase dimer from E. coli in complex with AMP.

Glycogen phosphorylase tetramer from E. coli in complex with AMP

The structure of phycobilisome with a bicylindrical core from the cyanobacterium Synechococcus elongatus PCC 7942

Cryo-EM structure of GGCX-PRGP1 complex

Cryo-EM structure of GGCX-FIX complex

Cryo-EM structure of GGCX-MGP complex

Cryo-EM structure of GGCX-proP2

The cryo-EM structure of PBS core from Synechococcus elongatus PCC 7942

The cryo-EM structure of PBS rod from synechococous elongatus PCC 7942

The structure of phycobilisome rod from Synechococcus elongatus PCC 7942

The cryo-EM structure of PBS from Synechococcus elongatus PCC 7942

The cryo-EM structure of PBS core from Synechococcus elongatus PCC 7942

The cryo-EM structure of PBS from Synechococcus elongatus PCC 7942

In-situ yeast 80S ribosome from sublimated samples

Structure of the Chlamydomonas reinhardtii chlororibosome with P-site tRNA

XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S head)

Cryo-EM structure of Dengue virus serotype2 US/BID-V594/2006 strain bound with J9 fab.

Helical Reconstruction of DENV2 THSTI/TRC/01 tubular particles bound with J9 fab

Structure of the Chlamydomonas reinhardtii chlororibosome with factor pY

Helical Reconstruction of DENV2 US/BID-V594/2006 tubular particles bound with J9 fab

XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S body)

PSI-LHCE-LHCII from Euglena gracilis

Cryo-EM structure of Dengue virus serotype2 THSTI/TRC/01 strain bound with J9 fab

Structure of Cytochrome C6 bound Photosystem I from Chlamydomonas reinhardtii at 2.07 A resolution

Structure of Photosystem I from Chlamydomonas reinhardtii at 1.83 A resolution

PSI-LHCE-LHCII from Euglena gracilis at 2.35 angstrom

RuvBL core from encounter state of SRCAP-nucleosome complex (focused refinement)

Cryo-EM model of E. coli aspartate transcarbamoylase in the T-state complexed with CP, CTP, and Mg2+

TRRAP lobe of the native human TIP60 complex, top region (focused refinement)

LhcbM4.10 of PSI-LHCE-LHCII from Euglena gracilis

RuvBL core from unbound SRCAP complex (focused refinement)

Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (consensus map filtered by local resolution)

RuvBL core from fully-engaged state of SRCAP-nucleosome complex (focused refinement)

ATPase module from fully-engaged state of SRCAP-nucleosome complex (focused refinement)

LhcE8(P2) of PSI-LHCE-LHCII from Euglena gracilis

Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (consensus map filtered by local resolution)

Nucleosome from fully-engaged state of SRCAP-nucleosome complex (focused refinement)

ARP6-ZNHIT1 module from fully-engaged state of SRCAP-nucleosome complex (focused refinement)

Cryo-EM structure of human SRCAP complex in the unbound state (consensus map filtered by local resolution)

RuvBL core from pre-engaged state of SRCAP-nucleosome complex (focused refinement)

ATPase module from partially-engaged state of SRCAP-nucleosome complex (focused refinement)

Nucleosome from pre-engaged state of SRCAP-nucleosome complex (focused refinement)

ARP6-ZNHIT1 module from encounter state of SRCAP-nucleosome complex (focused refinement)

ARP6-ZNHIT1 module from pre-engaged state of SRCAP-nucleosome complex (focused refinement)

Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (consensus map filtered by local resolution)

ARP6-ZNHIT1 module from unbound SRCAP complex (focused refinement)

RuvBL core from partially-engaged state of SRCAP-nucleosome complex (focused refinement)

ARP6-ZNHIT1 module from partially-engaged state of SRCAP-nucleosome complex (focused refinement)

Cryo-EM structure of human SRCAP-nucleosome complex in the encounter state (consensus map filtered by local resolution)

Nucleosome from partially-engaged state of SRCAP-nucleosome complex (focused refinement)

Nucleosome from encounter state of SRCAP-nucleosome complex (focused refinement)

SsoPfMCM:DNA class 1b from DNA 2

SsoPfMCM:DNA class 1a from DNA 2

ATPase module from encounter state of SRCAP-nucleosome complex (focused refinement)

SsoPfMCM:DNA class 1c from DNA 2

SsoPfMCM:DNA class 2a from DNA 2

SsoPfMCM:DNA class 2b from DNA 2

SsoPfMCM:DNA class 3 from DNA 2

RuvBL lobe of the native human TIP60 complex, HSA module (focused refinement)

Cryo-EM structure of the TRRAP lobe of the native human TIP60 complex (consensus map filtered by local resolution)

RuvBL lobe of the native human TIP60 complex, bottom RUVBL region (focused refinement)

RuvBL lobe of the native human TIP60 complex, top RUVBL region (focused refinement)

TRRAP lobe of the native human TIP60 complex, core region (focused refinement)

NER dual incision complex - NoG

TRRAP lobe of the native human TIP60 complex, distal region (focused refinement)

TRRAP lobe of the native human TIP60 complex, bottom region (focused refinement)

Cryo-EM structure of the RuvBL lobe of the native human TIP60 complex (consensus map filtered by local resolution)

High-resolution cryo-EM structure of KdpFABC in the E1P state in lipid nanodisc

High-resolution cryo-EM structure of KdpFABC in the E1-ATP state in lipid nanodisc

High-resolution cryo-EM structure of KdpFABC in the E1 state in lipid nanodisc

High-resolution cryo-EM structure of KdpFABC in the E2P state in lipid nanodisc

High-resolution cryo-EM structure of KdpFABC in the E2 state in lipid nanodisc

Cryo-EM structure of a membrane transport protein

CH35 gp41-FP macaque polyclonal Fab in complex with Q23-APEX-GT2 trimer

Structure of human annexin A1 in complex with 2C1 Fab

CCT G beta 5 G257E complex state 5

CCT G beta 5 R269E complex state 2

CCT G beta 5 G257E complex state 6

CH35 V1V2V3 and gp41-base macaque polyclonal Fabs in complex with Q23-APEX-GT2 trimer

CCT G beta 5 G257E complex state 2

CCT G beta 5 R269E complex state 5

Cryo-EM structure of V2 apex germline-targeting HIV Env trimer Q23-APEX-GT2

Cryo-EM structure of rat TRPM1 in the apo state

Cryo-EM structure of rhesus antibody CH70-Apex2.01 in complex with HIV Env trimer Q23-APEX-GT2

Cryo-EM structure of rhesus antibody CH42-Apex2.01 in complex with HIV Env trimer Q23-APEX-GT2

CH70 gp41-GH macaque polyclonal Fab in complex with Q23-APEX-GT2 trimer

CCT G beta 5 S123L complex state 2

CCT G beta 5 S123L complex state 3

CCT G beta 5 G257E complex state 1

CCT G beta 5 R269E complex state 1

CCT G beta 5 G257E complex state 4

CCT G beta 5 S123L complex state 1

CCT G beta 5 R269E complex state 3

CCT G beta 5 R269E complex state 4

CCT G beta 5 G257E complex state 3

Cryo-EM structure of rhesus antibody CI91-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2

Cryo-EM structure of rhesus antibody CH70-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2

Cryo-EM structure of rhesus antibody CH35-Apex1.08 in complex with HIV Env trimer Q23-APEX-GT2

CryoEM analysis of Phosphoglucose isomerase from P. aeruginosa reveals potential clinically relevant features

Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (370) Complex Bound by the MEDI3622 Fab

Cryo-EM structure of rhesus antibody CH42-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2

Single Particle Cryo EM Analysis of a Ribosome Nascent Globin Complex

Cryo-EM structure of a pentameric RAD51-XRCC3-RAD51C-RAD51D-XRCC2 (51-X3CDX2) complex.

Cryo-EM structure of an octameric RAD51-XRCC3-RAD51C (RAD51-X3C) complex

Octopus sensory receptor CRT1 bound to Progesterone

Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex

PSI-8 FCPI supercomplex from haptophyte Chrysotila roscoffensis

PSI-6 FCPI supercomplex from haptophyte Chrysotila roscoffensis

PSI-1 FCPI supercomplex from haptophyte Chrysotila roscoffensis

PSI-9 FCPI supercomplex from haptophyte Chrysotila roscoffensis

PSI-4 FCPI supercomplex from haptophyte Chrysotila roscoffensis

Cryo-EM structure of complex I on the bovine heart submitochondrial particles, closed

Cryo-EM structure of complex I on the bovine heart submitochondrial particles, open

Human 80S ribosome in complex with DHX29

Cryo-EM structure of FoF1-ATPase monomer state 3 on the bovine heart submitochondrial particles (FoF1-2)

Cryo-EM structure of FoF1-ATPase monomer state 1 on the bovine heart submitochondrial particles (FoF1-1)

Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-1

Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-B

Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-C

Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-2

Cryo-EM structure of Fo domain of FoF1-ATPase monomer state on the bovine heart submitochondrial particles

The complex of human pMEK1 and uERK1 (ANP)(from pY204ERK1)

The complex of human pMEK1 and uERK1 (ANP)

The complex of human pMEK1 and ERK1 pY204 (ANP)

The complex of human pMEK1 and ERK1 pT202 (ANP)

Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-A

Focus refined map of human SAGA TRRAP end

Human SAGA core Domain

BtCap14 SAVED domain + 2',3'-cGAMP

Cryo-EM structure of the human SAGA co-activator complex

Focus refined map of Human SAGA SF3B module

Human SAGA consensus map

Focus refined map of TRRAP in human SAGA

His-tagged Glutamine Synthetase on a Ni-NTA lipid monolayer grid

Full-length BG505 HIV-1 Env expressed in VLP