EMD-74043

Single-particle
1.9 Å
EMD-74043
3D View Gallery
Deposition: 24/11/2025
Map released: 01/04/2026
Last modified: 01/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74043

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zcw summary report (pdf.gz) Map-9zcw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the engineered vector AAV2.ATX002

EMD-74043

Single-particle
1.9 Å
EMD-74043
3D View Gallery
Deposition: 24/11/2025
Map released: 01/04/2026
Last modified: 01/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: adeno-associated virus 2
Sample: adeno-associated virus 2
Fitted models: 9zcw

Deposition Authors: Betegon M, Byrne LC, Conway JF

Structural dynamics insights into principles underlying the increased fitness of newly engineered and broadly potent AAV capsids
Johnson ME, Ozturk BE, Tugwell TH, Lambros M, Janowitz H, Sedorovitz M, Flohr K, Campello L, Hartung JE, Hogle B, Gillespie M, Schriever H, Aweidah H, Koester J, Clausen I, Seeber S, Revelant F, Schreurs R, Koechl F, Sieving PA, Sahel JA, Stauffer WR, Peixoto RT, Fauser S, Lin R, Conway J, Da Silva S, Krol J, Betegon M, Byrne LC
To Be Published