EMD-49866
Cryo-EM structure of rhesus antibody CH35-Apex1.08 in complex with HIV Env trimer Q23-APEX-GT2
EMD-49866
Single-particle3.3 Å
Deposition: 21/03/2025Map released: 01/04/2026
Last modified: 29/04/2026
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1
Sample: CH35-Apex1.08 Fab in complex with HIV envelope trimer
Fitted models: 9nvw
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Sample: CH35-Apex1.08 Fab in complex with HIV envelope trimer
Fitted models: 9nvw
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques.
Mishra N,
Liang B,
Roark RS,
Ghosh AR,
Callaghan S,
Lee WH,
Li X,
Vo AL,
Avillion G,
Chowdhury RR,
Habib R,
Bibollet-Ruche F,
Giese G,
Oberoi P,
Amereh K,
Somanathan A,
Zhu Y,
Zhang Y,
Kassab M,
Tjio L,
Andrabi S,
Reyes RA,
Allen JD,
James NE,
Randall Jr KN,
van der Maas L,
Ben-Akiva E,
Kacmarek-Michaels K,
Plante S,
Martella CL,
Skelly AN,
Singh A,
Hurtado J,
Dueker K,
Capozzola T,
Nedellec R,
Ozorowski G,
Lewis MG,
Falcone S,
Carfi A,
Himansu S,
Shapiro L,
Crispin M,
Hahn BH,
Briney B,
Irvine DJ,
Burton DR,
Ward AB,
Batista FD,
Kwong PD,
Shaw GM,
Andrabi R
(2026) Immunity , 59 , 1140 - 1160.e11
(2026) Immunity , 59 , 1140 - 1160.e11
Grant Support:
