EMD-49865
Cryo-EM structure of V2 apex germline-targeting HIV Env trimer Q23-APEX-GT2
EMD-49865
Single-particle2.9 Å
Deposition: 21/03/2025Map released: 01/04/2026
Last modified: 29/04/2026
Sample Organism:
Human immunodeficiency virus 1
Sample: HIV Env trimer Q23-APEX-GT2
Fitted models: 9nvv
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Sample: HIV Env trimer Q23-APEX-GT2
Fitted models: 9nvv
Deposition Authors: Roark RS, Shapiro LS, Kwong PD, Kwong PD
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques.
Mishra N,
Liang B,
Roark RS,
Ghosh AR,
Callaghan S,
Lee WH,
Li X,
Vo AL,
Avillion G,
Chowdhury RR,
Habib R,
Bibollet-Ruche F,
Giese G,
Oberoi P,
Amereh K,
Somanathan A,
Zhu Y,
Zhang Y,
Kassab M,
Tjio L,
Andrabi S,
Reyes RA,
Allen JD,
James NE,
Randall Jr KN,
van der Maas L,
Ben-Akiva E,
Kacmarek-Michaels K,
Plante S,
Martella CL,
Skelly AN,
Singh A,
Hurtado J,
Dueker K,
Capozzola T,
Nedellec R,
Ozorowski G,
Lewis MG,
Falcone S,
Carfi A,
Himansu S,
Shapiro L,
Crispin M,
Hahn BH,
Briney B,
Irvine DJ,
Burton DR,
Ward AB,
Batista FD,
Kwong PD,
Shaw GM,
Andrabi R
(2026) Immunity , 59 , 1140 - 1160.e11
(2026) Immunity , 59 , 1140 - 1160.e11
Grant Support:
