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CHEBI:45373 - sulfanilamide

ChEBI IDCHEBI:45373
ChEBI Namesulfanilamide
Stars
DefinitionA sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position.
Secondary ChEBI IDsCHEBI:9333, CHEBI:45370
Last Modified8 March 2019
DownloadsMolfile
FormulaC6H8N2O2S
Net Charge0
Average Mass172.209
Monoisotopic Mass172.03065
SMILESNc1ccc(S(N)(=O)=O)cc1
InChIInChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKeyFDDDEECHVMSUSB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
drug allergen  Any drug which causes the onset of an allergic reaction.
EC 4.2.1.1 (carbonic anhydrase) inhibitor  An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application:
drug allergen  Any drug which causes the onset of an allergic reaction.
ChEBI Ontology
Outgoing Relation(s)
sulfanilamide (CHEBI:45373) has role antibacterial agent (CHEBI:33282)
sulfanilamide (CHEBI:45373) has role drug allergen (CHEBI:88188)
sulfanilamide (CHEBI:45373) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018)
sulfanilamide (CHEBI:45373) is a substituted aniline (CHEBI:48975)
sulfanilamide (CHEBI:45373) is a sulfonamide (CHEBI:35358)
sulfanilamide (CHEBI:45373) is a sulfonamide antibiotic (CHEBI:87228)
Incoming Relation(s)
N-acetylsulfamethoxazole (CHEBI:31169) has functional parent sulfanilamide (CHEBI:45373)
4-sulfanilamidobenzoic acid (CHEBI:53237) has functional parent sulfanilamide (CHEBI:45373)
fosamprenavir (CHEBI:82941) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfadiazine (CHEBI:61018) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfamethoxazole (CHEBI:53017) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfapyridine (CHEBI:61023) has functional parent sulfanilamide (CHEBI:45373)
prontosil (CHEBI:8464) has functional parent sulfanilamide (CHEBI:45373)
sulfacetamide (CHEBI:63845) has functional parent sulfanilamide (CHEBI:45373)
sulfadiazine (CHEBI:9328) has functional parent sulfanilamide (CHEBI:45373)
sulfadiazine hydroxylamine (CHEBI:61017) has functional parent sulfanilamide (CHEBI:45373)
sulfadimethoxine (CHEBI:32161) has functional parent sulfanilamide (CHEBI:45373)
sulfamerazine (CHEBI:102130) has functional parent sulfanilamide (CHEBI:45373)
sulfamethazine (CHEBI:102265) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxazole (CHEBI:9332) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxazole hydroxylamine (CHEBI:53016) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxydiazine (CHEBI:53727) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxypyridazine (CHEBI:102516) has functional parent sulfanilamide (CHEBI:45373)
sulfapyridine (CHEBI:132842) has functional parent sulfanilamide (CHEBI:45373)
sulfapyridine hydroxylamine (CHEBI:61021) has functional parent sulfanilamide (CHEBI:45373)
sulfasalazine (CHEBI:9334) has functional parent sulfanilamide (CHEBI:45373)
sulfathiazole (CHEBI:9337) has functional parent sulfanilamide (CHEBI:45373)
sulfathiourea (CHEBI:131723) has functional parent sulfanilamide (CHEBI:45373)
sulfisomidine (CHEBI:32166) has functional parent sulfanilamide (CHEBI:45373)
sulfisoxazole (CHEBI:102484) has functional parent sulfanilamide (CHEBI:45373)
IUPAC Name 
4-aminobenzenesulfonamide
Synonyms  Source
SulfanilamideKEGG COMPOUND
p-aminobenzenesulfamideNIST Chemistry WebBook
SULFANILAMIDEPDBeChem
StreptocideNIST Chemistry WebBook
p-aminobenzenesulfonamideNIST Chemistry WebBook
sulfamineNIST Chemistry WebBook
Manual XrefsDatabases
C07458KEGG COMPOUND
SANPDBeChem
SulfanilamideWikipedia
DB00259DrugBank
HMDB0014404HMDB
D08543KEGG DRUG
LSM-6524LINCS
2521DrugCentral
1924VSDB
Registry NumbersSources
Gmelin:83068Gmelin
Beilstein:511852Beilstein
Reaxys:511852Reaxys
CAS:63-74-1KEGG COMPOUND
CAS:63-74-1ChemIDplus
CAS:63-74-1NIST Chemistry WebBook
Citations