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CHEBI:45373 - sulfanilamide

ChEBI IDCHEBI:45373
ChEBI Namesulfanilamide
Stars
DefinitionA sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position.
Secondary ChEBI IDsCHEBI:9333, CHEBI:45370
Last Modified8 March 2019
DownloadsMolfile
FormulaC6H8N2O2S
Net Charge0
Average Mass172.209
Monoisotopic Mass172.03065
SMILESNc1ccc(S(N)(=O)=O)cc1
InChIInChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKeyFDDDEECHVMSUSB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
EC 4.2.1.1 (carbonic anhydrase) inhibitor  An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule.
drug allergen  Any drug which causes the onset of an allergic reaction.
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application:
drug allergen  Any drug which causes the onset of an allergic reaction.
ChEBI Ontology
Outgoing Relation(s)
sulfanilamide (CHEBI:45373) has role antibacterial agent (CHEBI:33282)
sulfanilamide (CHEBI:45373) has role drug allergen (CHEBI:88188)
sulfanilamide (CHEBI:45373) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018)
sulfanilamide (CHEBI:45373) is a substituted aniline (CHEBI:48975)
sulfanilamide (CHEBI:45373) is a sulfonamide (CHEBI:35358)
sulfanilamide (CHEBI:45373) is a sulfonamide antibiotic (CHEBI:87228)
Incoming Relation(s)
N-acetylsulfamethoxazole (CHEBI:31169) has functional parent sulfanilamide (CHEBI:45373)
4-sulfanilamidobenzoic acid (CHEBI:53237) has functional parent sulfanilamide (CHEBI:45373)
fosamprenavir (CHEBI:82941) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfadiazine (CHEBI:61018) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfamethoxazole (CHEBI:53017) has functional parent sulfanilamide (CHEBI:45373)
nitrososulfapyridine (CHEBI:61023) has functional parent sulfanilamide (CHEBI:45373)
prontosil (CHEBI:8464) has functional parent sulfanilamide (CHEBI:45373)
sulfacetamide (CHEBI:63845) has functional parent sulfanilamide (CHEBI:45373)
sulfadiazine (CHEBI:9328) has functional parent sulfanilamide (CHEBI:45373)
sulfadiazine hydroxylamine (CHEBI:61017) has functional parent sulfanilamide (CHEBI:45373)
sulfadimethoxine (CHEBI:32161) has functional parent sulfanilamide (CHEBI:45373)
sulfamerazine (CHEBI:102130) has functional parent sulfanilamide (CHEBI:45373)
sulfamethazine (CHEBI:102265) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxazole (CHEBI:9332) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxazole hydroxylamine (CHEBI:53016) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxydiazine (CHEBI:53727) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxypyridazine (CHEBI:102516) has functional parent sulfanilamide (CHEBI:45373)
sulfapyridine (CHEBI:132842) has functional parent sulfanilamide (CHEBI:45373)
sulfapyridine hydroxylamine (CHEBI:61021) has functional parent sulfanilamide (CHEBI:45373)
sulfasalazine (CHEBI:9334) has functional parent sulfanilamide (CHEBI:45373)
sulfathiazole (CHEBI:9337) has functional parent sulfanilamide (CHEBI:45373)
sulfathiourea (CHEBI:131723) has functional parent sulfanilamide (CHEBI:45373)
sulfisomidine (CHEBI:32166) has functional parent sulfanilamide (CHEBI:45373)
sulfisoxazole (CHEBI:102484) has functional parent sulfanilamide (CHEBI:45373)
IUPAC Name 
4-aminobenzenesulfonamide
Synonyms  Source
SulfanilamideKEGG COMPOUND
p-aminobenzenesulfamideNIST Chemistry WebBook
SULFANILAMIDEPDBeChem
StreptocideNIST Chemistry WebBook
p-aminobenzenesulfonamideNIST Chemistry WebBook
sulfamineNIST Chemistry WebBook
Manual XrefsDatabases
C07458KEGG COMPOUND
SANPDBeChem
SulfanilamideWikipedia
DB00259DrugBank
HMDB0014404HMDB
D08543KEGG DRUG
LSM-6524LINCS
2521DrugCentral
1924VSDB
Registry NumbersSources
Gmelin:83068Gmelin
Beilstein:511852Beilstein
Reaxys:511852Reaxys
CAS:63-74-1KEGG COMPOUND
CAS:63-74-1ChemIDplus
CAS:63-74-1NIST Chemistry WebBook
Citations