CHEBI:63845 - sulfacetamide

ChEBI IDCHEBI:63845
ChEBI Namesulfacetamide
Stars
DefinitionA sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC8H10N2O3S
Net Charge0
Average Mass214.246
Monoisotopic Mass214.04121
SMILESCC(=O)NS(=O)(=O)c1ccc(N)cc1
InChIInChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
InChIKeySKIVFJLNDNKQPD-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
EC 2.5.1.15 (dihydropteroate synthase) inhibitor  An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
antibacterial drug  A drug used to treat or prevent bacterial infections.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Applications:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
antibacterial drug  A drug used to treat or prevent bacterial infections.
ChEBI Ontology
Outgoing Relation(s)
sulfacetamide (CHEBI:63845) has functional parent sulfanilamide (CHEBI:45373)
sulfacetamide (CHEBI:63845) has role antibacterial drug (CHEBI:36047)
sulfacetamide (CHEBI:63845) has role antiinfective agent (CHEBI:35441)
sulfacetamide (CHEBI:63845) has role antimicrobial agent (CHEBI:33281)
sulfacetamide (CHEBI:63845) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502)
sulfacetamide (CHEBI:63845) is a N-sulfonylcarboxamide (CHEBI:90852)
sulfacetamide (CHEBI:63845) is a substituted aniline (CHEBI:48975)
sulfacetamide (CHEBI:63845) is conjugate acid of sulfacetamide(1−) (CHEBI:63857)
Incoming Relation(s)
sulfacetamide(1−) (CHEBI:63857) is conjugate base of sulfacetamide (CHEBI:63845)
IUPAC Name 
N-[(4-aminophenyl)sulfonyl]acetamide
INNs  Source
sulfacetamideKEGG DRUG
sulfacetamidaChemIDplus
sulfacetamidumChemIDplus
Synonyms  Source
p-AminobenzenesulfonacetamideDrugBank
N'-AcetylsulfanilamideDrugBank
N-AcetylsulfanilamideDrugBank
N-SulfanilylacetamideDrugBank
N1-acetylsulfanilamideChemIDplus
N1-acetyl-4-aminophenylsulfonamideChemIDplus
Manual XrefsDatabases
D05947KEGG DRUG
DB00634DrugBank
SulfacetamideWikipedia
LSM-5374LINCS
2497DrugCentral
Registry NumbersSources
Reaxys:981718Reaxys
CAS:144-80-9ChemIDplus
CAS:144-80-9NIST Chemistry WebBook
Citations