EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:9332 - sulfamethoxazole
| Formula | C10H11N3O3S |
| Net Charge | 0 |
| Average Mass | 253.283 |
| Monoisotopic Mass | 253.05211 |
| SMILES | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 |
| InChI | InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13) |
| InChIKey | JLKIGFTWXXRPMT-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. EC 2.5.1.15 (dihydropteroate synthase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. drug allergen Any drug which causes the onset of an allergic reaction. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | drug allergen Any drug which causes the onset of an allergic reaction. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sulfamethoxazole (CHEBI:9332) has functional parent sulfanilamide (CHEBI:45373) |
| sulfamethoxazole (CHEBI:9332) has role antibacterial agent (CHEBI:33282) |
| sulfamethoxazole (CHEBI:9332) has role antiinfective agent (CHEBI:35441) |
| sulfamethoxazole (CHEBI:9332) has role antimicrobial agent (CHEBI:33281) |
| sulfamethoxazole (CHEBI:9332) has role drug allergen (CHEBI:88188) |
| sulfamethoxazole (CHEBI:9332) has role EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor (CHEBI:74234) |
| sulfamethoxazole (CHEBI:9332) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502) |
| sulfamethoxazole (CHEBI:9332) has role environmental contaminant (CHEBI:78298) |
| sulfamethoxazole (CHEBI:9332) has role epitope (CHEBI:53000) |
| sulfamethoxazole (CHEBI:9332) has role P450 inhibitor (CHEBI:50183) |
| sulfamethoxazole (CHEBI:9332) has role xenobiotic (CHEBI:35703) |
| sulfamethoxazole (CHEBI:9332) is a isoxazoles (CHEBI:55373) |
| sulfamethoxazole (CHEBI:9332) is a substituted aniline (CHEBI:48975) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide (CHEBI:35358) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide antibiotic (CHEBI:87228) |
| Incoming Relation(s) |
| N-acetylsulfamethoxazole (CHEBI:31169) has functional parent sulfamethoxazole (CHEBI:9332) |
| nitrososulfamethoxazole (CHEBI:53017) has functional parent sulfamethoxazole (CHEBI:9332) |
| sulfamethoxazole hydroxylamine (CHEBI:53016) has functional parent sulfamethoxazole (CHEBI:9332) |
| co-trimoxazole (CHEBI:3770) has part sulfamethoxazole (CHEBI:9332) |
| IUPAC Name |
|---|
| 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide |
| Synonyms | Source |
|---|---|
| 3-(p-Aminophenylsulfonamido)-5-methylisoxazole | ChemIDplus |
| 3-Sulfanilamido-5-methylisoxazole | ChemIDplus |
| 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide | ChemIDplus |
| Gantanol (TN) | KEGG DRUG |
| SMX | ChEBI |
| Sulfamethoxazole | KEGG COMPOUND |
| Manual Xrefs | Databases |
|---|---|
| 2514 | DrugCentral |
| C07315 | KEGG COMPOUND |
| D00447 | KEGG DRUG |
| DB01015 | DrugBank |
| HMDB0015150 | HMDB |
| LSM-5422 | LINCS |
| Sulfamethoxazole | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:226453 | Reaxys |
| Gmelin:226453 | Gmelin |
| CAS:723-46-6 | DrugBank |
| CAS:723-46-6 | KEGG COMPOUND |
| CAS:723-46-6 | ChemIDplus |
| Citations |
|---|