EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:9332 - sulfamethoxazole
| Formula | C10H11N3O3S |
| Net Charge | 0 |
| Average Mass | 253.283 |
| Monoisotopic Mass | 253.05211 |
| SMILES | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 |
| InChI | InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13) |
| InChIKey | JLKIGFTWXXRPMT-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin. epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. EC 2.5.1.15 (dihydropteroate synthase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. drug allergen Any drug which causes the onset of an allergic reaction. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | drug allergen Any drug which causes the onset of an allergic reaction. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sulfamethoxazole (CHEBI:9332) has functional parent sulfanilamide (CHEBI:45373) |
| sulfamethoxazole (CHEBI:9332) has role antibacterial agent (CHEBI:33282) |
| sulfamethoxazole (CHEBI:9332) has role antiinfective agent (CHEBI:35441) |
| sulfamethoxazole (CHEBI:9332) has role antimicrobial agent (CHEBI:33281) |
| sulfamethoxazole (CHEBI:9332) has role drug allergen (CHEBI:88188) |
| sulfamethoxazole (CHEBI:9332) has role EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor (CHEBI:74234) |
| sulfamethoxazole (CHEBI:9332) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502) |
| sulfamethoxazole (CHEBI:9332) has role environmental contaminant (CHEBI:78298) |
| sulfamethoxazole (CHEBI:9332) has role epitope (CHEBI:53000) |
| sulfamethoxazole (CHEBI:9332) has role P450 inhibitor (CHEBI:50183) |
| sulfamethoxazole (CHEBI:9332) has role xenobiotic (CHEBI:35703) |
| sulfamethoxazole (CHEBI:9332) is a isoxazoles (CHEBI:55373) |
| sulfamethoxazole (CHEBI:9332) is a substituted aniline (CHEBI:48975) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide (CHEBI:35358) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide antibiotic (CHEBI:87228) |
| Incoming Relation(s) |
| N-acetylsulfamethoxazole (CHEBI:31169) has functional parent sulfamethoxazole (CHEBI:9332) |
| nitrososulfamethoxazole (CHEBI:53017) has functional parent sulfamethoxazole (CHEBI:9332) |
| sulfamethoxazole hydroxylamine (CHEBI:53016) has functional parent sulfamethoxazole (CHEBI:9332) |
| co-trimoxazole (CHEBI:3770) has part sulfamethoxazole (CHEBI:9332) |
| IUPAC Name |
|---|
| 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide |
| Synonyms | Source |
|---|---|
| 3-(p-Aminophenylsulfonamido)-5-methylisoxazole | ChemIDplus |
| 3-Sulfanilamido-5-methylisoxazole | ChemIDplus |
| 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide | ChemIDplus |
| Gantanol (TN) | KEGG DRUG |
| SMX | ChEBI |
| Sulfamethoxazole | KEGG COMPOUND |
| Manual Xrefs | Databases |
|---|---|
| 2514 | DrugCentral |
| C07315 | KEGG COMPOUND |
| D00447 | KEGG DRUG |
| DB01015 | DrugBank |
| HMDB0015150 | HMDB |
| LSM-5422 | LINCS |
| Sulfamethoxazole | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:226453 | Reaxys |
| Gmelin:226453 | Gmelin |
| CAS:723-46-6 | DrugBank |
| CAS:723-46-6 | KEGG COMPOUND |
| CAS:723-46-6 | ChemIDplus |
| Citations |
|---|