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CHEBI:9332 - sulfamethoxazole
| Formula | C10H11N3O3S |
| Net Charge | 0 |
| Average Mass | 253.283 |
| Monoisotopic Mass | 253.05211 |
| SMILES | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 |
| InChI | InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13) |
| InChIKey | JLKIGFTWXXRPMT-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. EC 2.5.1.15 (dihydropteroate synthase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. drug allergen Any drug which causes the onset of an allergic reaction. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. renoprotective agent Any compound that is able to prevent damage to the kidneys. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. drug allergen Any drug which causes the onset of an allergic reaction. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. hypoglycemic agent A drug which lowers the blood glucose level. antifibrotic agent Any agent which acts to reduce fibrosis. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| sulfamethoxazole (CHEBI:9332) has functional parent sulfanilamide (CHEBI:45373) |
| sulfamethoxazole (CHEBI:9332) has role anti-HIV agent (CHEBI:64946) |
| sulfamethoxazole (CHEBI:9332) has role antibacterial agent (CHEBI:33282) |
| sulfamethoxazole (CHEBI:9332) has role antifibrotic agent (CHEBI:233423) |
| sulfamethoxazole (CHEBI:9332) has role antifungal agent (CHEBI:35718) |
| sulfamethoxazole (CHEBI:9332) has role antiinfective agent (CHEBI:35441) |
| sulfamethoxazole (CHEBI:9332) has role antimalarial (CHEBI:38068) |
| sulfamethoxazole (CHEBI:9332) has role antimicrobial agent (CHEBI:33281) |
| sulfamethoxazole (CHEBI:9332) has role antimicrobial agent (CHEBI:33281) |
| sulfamethoxazole (CHEBI:9332) has role antineoplastic agent (CHEBI:35610) |
| sulfamethoxazole (CHEBI:9332) has role antitubercular agent (CHEBI:33231) |
| sulfamethoxazole (CHEBI:9332) has role dermatologic drug (CHEBI:50177) |
| sulfamethoxazole (CHEBI:9332) has role drug allergen (CHEBI:88188) |
| sulfamethoxazole (CHEBI:9332) has role EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor (CHEBI:74234) |
| sulfamethoxazole (CHEBI:9332) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502) |
| sulfamethoxazole (CHEBI:9332) has role environmental contaminant (CHEBI:78298) |
| sulfamethoxazole (CHEBI:9332) has role epitope (CHEBI:53000) |
| sulfamethoxazole (CHEBI:9332) has role hypoglycemic agent (CHEBI:35526) |
| sulfamethoxazole (CHEBI:9332) has role ophthalmology drug (CHEBI:66981) |
| sulfamethoxazole (CHEBI:9332) has role P450 inhibitor (CHEBI:50183) |
| sulfamethoxazole (CHEBI:9332) has role renoprotective agent (CHEBI:231911) |
| sulfamethoxazole (CHEBI:9332) has role xenobiotic (CHEBI:35703) |
| sulfamethoxazole (CHEBI:9332) is a isoxazoles (CHEBI:55373) |
| sulfamethoxazole (CHEBI:9332) is a substituted aniline (CHEBI:48975) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide (CHEBI:35358) |
| sulfamethoxazole (CHEBI:9332) is a sulfonamide antibiotic (CHEBI:87228) |
| Incoming Relation(s) |
| N-acetylsulfamethoxazole (CHEBI:31169) has functional parent sulfamethoxazole (CHEBI:9332) |
| nitrososulfamethoxazole (CHEBI:53017) has functional parent sulfamethoxazole (CHEBI:9332) |
| sulfamethoxazole hydroxylamine (CHEBI:53016) has functional parent sulfamethoxazole (CHEBI:9332) |
| co-trimoxazole (CHEBI:3770) has part sulfamethoxazole (CHEBI:9332) |
| IUPAC Name |
|---|
| 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide |
| INN | Source |
|---|---|
| sulfametoxazol | WHO MedNet |
| Synonyms | Source |
|---|---|
| 3-(p-Aminophenylsulfonamido)-5-methylisoxazole | ChemIDplus |
| 3-Sulfanilamido-5-methylisoxazole | ChemIDplus |
| 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide | ChemIDplus |
| Gantanol (TN) | KEGG DRUG |
| NSC-147832 | ChEMBL |
| RO 4-2130 | ChEMBL |
| Brand Names | Source |
|---|---|
| Gantanol | ChEMBL |
| Gantanol-ds | ChEMBL |
| Sinomin | ChEMBL |
| Sulfamethoxazole component of azo gantanol | ChEMBL |
| Sulfamethoxazole component of bactrim | ChEMBL |
| Sulfamethoxazole component of bactrim ds | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 2514 | DrugCentral |
| C07315 | KEGG COMPOUND |
| D00447 | KEGG DRUG |
| DB01015 | DrugBank |
| HMDB0015150 | HMDB |
| LSM-5422 | LINCS |
| Sulfamethoxazole | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:226453 | Reaxys |
| Gmelin:226453 | Gmelin |
| CAS:723-46-6 | KEGG COMPOUND |
| CAS:723-46-6 | DrugBank |
| CAS:723-46-6 | ChemIDplus |
| Citations |
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