Ternary complex structure of compound 1 bound to SMARCA2 bromodomain and DCAF16:DDB1deltaBPB

Cryo-EM structure of the Class 3 PI3K alpha/KRas complex on POPC/POPS nanodiscs

Cryo-EM structure of the PI3K alpha/KRas complex on POPC/POPS/PIP2 nanodiscs low-pass filtered to 5 angstroms

Cryo-EM structure of active mutant human green cone opsin (E129Q) in complex with chimeric G protein (miniGist)

S.mutans Phosphodiesterase GdpP in the Presence of HEME-Cyanide

Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(C2)

Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(C1)

Local refinement of active human green opsin mutant E129Q in complex with chimeric G protein

Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(2_1)

Single particle reconstruction of PilU from Vibrio cholerae El Tor E7946, form 2

Single particle reconstruction of PilU from Vibrio cholerae El Tor E7946, form 4

S. mutans Phosphodiesterase GdpP with 5' pApA

S.mutans Phosphodiesterase GdpP in Apo State

Single particle reconstruction of PilU from Vibrio cholerae El Tor E7946, form 3

Single particle reconstruction of PilU from Vibrio cholerae El Tor E7946, form 1

Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B

Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) and hygromycin B, Class II

Structure of Geobacillus stearothermophilus RNase P ribozyme

Structure of Geobacillus stearothermophilus RNase P ribozyme sub-conformation 3

Structure of Geobacillus stearothermophilus RNase P ribozyme in 5 mM Mg2+

Structure of Geobacillus stearothermophilus RNase P ribozyme sub-conformation 1

Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with precursor tRNA in 5 mM Ca2+

Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with mature tRNA in 5 mM Ca2+

Structure of Geobacillus stearothermophilus RNase P ribozyme tetraloop mutant (sub-conformation 2)

Structure of Geobacillus stearothermophilus RNase P ribozyme in 10 mM Mg2+

Structure of Geobacillus stearothermophilus RNase P ribozyme tetraloop mutant (sub-conformation 1)

Abeta-42-Met35-(R)-SO - class2

A-beta42-Met-R-SO amyloidal fibril - class3

Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with mature tRNA in 10 mM Ca2+

Structure of Geobacillus stearothermophilus RNase P ribozyme sub-conformation 2

Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex (G protein-focused map)

Cryo-EM structure of the BW245C-bound prostaglandin D2 receptor (DP1)-Gs complex (Receptor-focused map)

Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex (Consensus map)

Cryo-EM structure of the BW245C-bound prostaglandin D2 receptor (DP1)-Gs complex (Consensus map)

Structure of Geobacillus stearothermophilus RNase P ribozyme tetraloop mutant (sub-conformation 3)

Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex (Receptor-focused map)

Cryo-EM structure of Pseudomonas aeruginosa outer-membrane lipoprotein PA3214 in the open conformation

Two Component Protein Nano-Particle (T=3). De Novo Design, Computationally Relaxed into Low Resolution Single Particle CryoEM Map with Icosahedral Symmetry Applied

Cryo-EM structure of the BW245C-bound prostaglandin D2 receptor (DP1)-Gs complex (G protein-focused map)

PA3213 MCE protein in complex with PA3214 OM lipoprotein

Cryo-EM structure of Pseudomonas aeruginosa soluble lipoprotein PA3214

Cryo-EM structure of Pseudomonas aeruginosa outer-membrane lipoprotein PA3214 bound to MCE protein PA3213 C-terminal peptide (CASP target)

Locally refined DeepEMhanced map of the meizothrombinDESF1-factor Xa complex

RNA Vault waist region, focused refinement (MVP/TEP1 sample)

Composite map of the meizothrombinDESF1, factor Xa and factor Va complex

Locally refined DeepEMhanced map of the factor Xa-factor Va complex

Human apo HCN1 nanodisc

Human HCN1 in complex with cAMP in nanodisc

RNA Vault cap (MVP/PARP4/TEP1 sample)

RNA Vault Shoulder with ADPR bound, compact conformation, focused refinement (MVP/PARP4/TEP1 NADP sample)

KpSwz in complex with bacteriophage Bas14 Portal

KpSwz DUF4062 (Hexamer, catalytic mutant E97A)

Composite map of hypomethylated 80S ribosome treated with hygromycin B

RNA Vault intermediate conformation (MVP/PARP4/TEP1 sample)

Human GATOR2 complex - Sestrin2 bound state

RNA Vault bound to PARP4 MINT, focused refinement (MVP/PARP4/TEP1 NADP sample)

Human GATOR2 complex - apo state

Human GATOR2 complex - CASTOR1 bound state

KpSwz DUF4062 (Tetramer, catalytic mutant E97A)

Human Brain RNA Vault Shoulder bound to ADPR, focused refinement (EMPIAR-10766)

Consensus map of the meizothrombinDESF1, factor Xa, factor Va complex

RNA Vault shoulder region with BAD bound, focused refinement (MVP/TEP1 sample)

RNA Vault extended conformation (MVP/PARP4/TEP1 sample)

RNA Vault Shoulder with ADPR bound, extended conformation, focused refinement (MVP/PARP4/TEP1 NADP sample)

RNA Vault with BAD bound (MVP/TEP1 sample)

RNA Vault with ADPR bound (MVP/PARP4/TEP1 NADP sample)

Flat clathrin lattice on endosomes

Ku70/80 bound to WRN-exo

Cryo-electron tomogram of endosomes in HeLa cells

Structure of the 70S ribosome with E- and P-site tRNA from the alphaproteobacteria Asaia platycodi.

Map of the 70S ribosome with E-site tRNA and HPF from the alphaproteobacteria Rhodospirillum rubrum.

Map of the 70S ribosome with E- and P-site tRNA from the gammaproteobacteria Escherichia coli.

Map of the 70S ribosome with E-site tRNA and HPF from the gammaproteobacteria Escherichia coli.

Map of the 70S ribosome with E- and P-site tRNA from the alphaproteobacteria Rhodospirillum rubrum.

Two Component Protein Nano-Particle (T=3). De Novo Design, Computationally Relaxed into Low Resolution Subtomogram Averaged CryoEM Map with Icosahedral Symmetry Applied

Structure of a stalled E. coli 70S RNC-NuoK-48 in complex with the SecYEG Translocon.

Quinpirole-bound Dopamine D3 Receptor - Gi Protein Complex

Buspirone-bound serotonin 5-HT1A receptor - Gi Protein Complex

Structure of a stalled E. coli 70S RNC-NuoK-48 in complex with the SecYEG Translocon (Focused Refinement)

Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the SecYEG-YidC membrane protein insertase (Focused Refinement)

Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the SecYEG-YidC membrane protein insertase

Structure of a stalled E. coli 70S RNC-NuoK-86-E36K-E76K-mutant in complex with the SecYEG-YidC membrane protein insertase (Focused Refinement)

Structure of a stalled E. coli 70S RNC-NuoK-86-E36K-E76K-mutant in complex with the SecYEG-YidC membrane protein insertase

Human FAM118B(24-334) hexameric filament

Focused map of LRRC58-CDO1 region from LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Structure of the human inner kinetochore CCAN bound to DNA

Focused map of ARIH1-Ub region from LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Focused map of LRRC58-CDO1 region from LRRC58-ELOB/C-CDO1-CUL5-RBX2-NEDD8-ARIH2-UB

Consensus Map of LRRC58-ELOB/C-CDO1 in complex with NEDD8-CUL5-RBX2-ARIH2-Ub

Structure of the human inner kinetochore CCAN bound to a mono-CENP-A nucleosome

Consensus map of LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Structure of the human inner kinetochore CCAN bound to a 3' CENP-A nucleosome

Structure of the human inner kinetochore CCAN bound to a 5' CENP-A nucleosome

Focused map of CUL2-LRRC58-EloC interface region from LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Structure of LRRC58-EloB/C-CDO1 in complex with NEDD8-CUL5-RBX2-ARIH2-Ub

1.80 A cryo-EM structure of Mycobacterium tuberculosis BfrB prepared under isotope-depleted abundance

Structure of the human inner kinetochore CCAN bound to a di-CENP-A nucleosome

1.79 A cryo-EM structure of Mycobacterium tuberculosis BfrB prepared under natural isotope abundance

Structure of the human inner kinetochore CCAN bound to a di-CENP-A nucleosome, consensus map

Structure of the human inner kinetochore CCAN and CENP-C bound to DNA

CryoEM structure of native quinol dependent Nitric Oxide Reductase with HQN at pH 6.5

CryoEM structure of native quinol dependent Nitric Oxide Reductase at pH 8.0.

CryoEM structure of quinol dependent Nitric Oxide Reductase with BRIL

AR234958 bound Mas1 Receptor

AR234958 bound Mas1 Receptor Complex

Cannabinoid Receptor 1-Gi Complex

Cryo-EM structure of DddT G101D in substrate-free outward open conformation

Cryo-EM structure of DddT in closed substrate-free conformation

Cannabinoid Receptor 1-Gi Complex

Cryo-EM structure of DddT in closed DMSP-bound conformation

Cryo-EM structure of human Nav1.6 in complex with Cn2

Cryo-EM structure of DddT G101D in substrate-free inward open conformation

Cryo-EM structure of human Nav1.6 in complex with Iota-Conotoxin RXIA

Cryo-EM structure of DddT in closed substrate-free conformation in the presence of potassium ions and dimethylsulfoniopropionate

Cryo-EM structure of human Nav1.6 in complex with delta-paraponeritoxin-Pc1a

Electron tomogram of resin-embedded yeast cells expressing Tcb3(1-272)-GFP-chimeraC, deleted for tcb1/2, scs2/22 and ist2

Structure of human MCM2-7 single hexamer without MCM3 CTE, state 2

Cryo-EM map of Suv3 monomer

Cryo-EM structure of dimeric Suv3-ADP complex

Structure of human MCM2-7 single hexamer without MCM3 CTE, state 1

Cryo-EM structure of monomeric Suv3-ssRNA complex

CryoEM structure of Arabidopsis thaliana Col-0 Rubisco with D4 symmetry

Structure of human MCM2-7 single hexamer with MCM3-WHD attached to MCM2-CTD

Cryo-EM structure of Dimeric Suv3-ssRNA-AMPPNP complex

Cryo-EM map of dimeric Suv3-ssRNA complex

Cryo-EM structure of monomeric Suv3-ADP complex

Cryo-EM map of Suv3 dimer

Cryo-EM map of monomeric Suv3-ssRNA-AMPPNP complex

Structure of human MCM2-7 single hexamer with MCM3-WHD attached to MCM2-CTD, state 2

Structure of human MCM2-7 single hexamer with MCM3-WHD attached to MCM2-CTD, state 3

Structure of human MCM2-7 single hexamer with MCM3-WHD attached to MCM2-CTD, containing Meier-Gorlin Syndrome mutation (MCM3-Q761L)

CryoEM structure of Arabidopsis thaliana M309I Rubisco with D4 symmetry

CryoEM structure of Arabidopsis thaliana D397N Rubisco with D4 symmetry

Asymmetric reconstruction of TBEV virion

Composite map of LRRC58- EloB/C-CDO1 in complex with neddylated CUL2-RBX1-ARIH1-Ub

Asymmetric reconstruction of immature TBEV particle with 2 missing pentamers

Phage 812 baseplate in the pre-contraction state (C1)

Cryo-EM structure of ComEC from Neomoorella carbonis

Phage 812 baseplate in the pre-contraction state (C3)

Asymmetric reconstruction of immature TBEV particle with 2 irregularities

Cryo-EM structure of Beta-lactamase-like domain from Neomoorella carbonis

Immature TBEV envelope spike with interaction partners underneath - SPA

Asymmetric reconstruction of immature TBEV particle with altered 5-fold

Immature TBEV envelope spike with interaction partners underneath - STA

Phage 812 baseplate in the pre-contraction state - upper arm (segment B)

Phage 812 baseplate in the pre-contraction state - core and wedge module proteins

Phage 812 baseplate in the pre-contraction state - lower arm (segment C)

Phage 812 baseplate in the pre-contraction state - lower arm (lRBP1-uRBP2)

Phage 812 baseplate in the pre-contraction state - lower arm (uRBP1-lRBP2)

Phage 812 baseplate in the pre-contraction state - lower arm (segment DEF)

Phage 812 baseplate in the pre-contraction state - upper arm (segment CDEF)

Phage 812 baseplate in the pre-contraction state - lower arm (segment B)

Phage 812 baseplate in the pre-contraction state - upper arm

Phage 812 baseplate in the pre-contraction state - upper arm (segment A)

Phage 812 baseplate in the pre-contraction state - tail sheath initiator and baseplate-proximal tail proteins

Phage 812 baseplate in the post-contraction state (C1)

Phage 812 baseplate in the pre-contraction state - lower arm (segment A)

Phage 812 baseplate in the post-contraction state (C6)

Phage 812 baseplate in the pre-contraction state - lower arm

Baseplate arm (segment B) of phage 812 in the post-contraction state

Phage 812 baseplate in the pre-contraction state - composite

Baseplate arm of phage 812 in the post-contraction state

Phage 812 baseplate in the post-contraction state - composite

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, with A/P- and P/E-site tRNA

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, with A- and P-site tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A/P- and P/E-site tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, with A/P- and P/E-site tRNA

E. coli 70S ribosome with A- and P-site tRNA

E. coli 70S ribosome with A/P- and P/E-site tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, with A- and P-site tRNA

E. coli 70S ribosome without tRNA

E. coli 70S ribosome with P-site tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with P-site tRNA

E. coli 70S ribosome with A- and P/E-site tRNA

E. coli 70S ribosome with P/E-site tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, with A- and P-site tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, with A/P- and P/E-site tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P/E-site tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, without tRNA

E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with P/E-site tRNA

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, with P-site tRNA

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, without tRNA

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, with A- and P/E-site tRNA

E. coli 70S ribosome, trapped conformational excited state of SSU-h44 apical loop, with P/E-site tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, with A- and P/E-site tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, without tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, with A- and P/E-site tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, with P-site tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, without tRNA

E. coli 70S ribosome, conformational ground state mutation in SSU-h41, with P/E-site tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, with P-site tRNA

E. coli 70S ribosome, conformational excited state mutation in SSU-h41, with P/E-site tRNA

Cryo-EM structure of MasR(FL)-Gq

Cryo-EM structure of MasR(del2-25)-Gq

Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with G51D mutaion in SNCA

Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with H50Q variant in SNCA

N. brasiliensis GlfT2 in a styrene maleic acid liponanoparticle (C1 Unmasked Map)

N. brasiliensis GlfT2 in a styrene maleic acid liponanoparticle

Structure of Rapidly twisting Amyloid-beta 40 fibril , RT-Ab40(C1)'