EMD-80134

Single-particle
2.5 Å
EMD-80134
3D View Gallery
Deposition: 06/04/2026
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80134
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 25ii summary report (pdf.gz) Map and 25ii FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Nav1.6 in complex with Iota-Conotoxin RXIA

EMD-80134

Single-particle
2.5 Å
EMD-80134
3D View Gallery
Deposition: 06/04/2026
Map released: 20/05/2026
Last modified: 20/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Conus radiatus
Sample: Nav1.6-Iota-conotoxin RXIA
Fitted models: 25ii

Deposition Authors: Fan X, Huang J, Yan N

Diverse modulation mechanisms of human Nav1.6 by gating modifier neurotoxins
Fan X, Jian H, Yang L, Chen J, Wang H, Huang X, Geng J, Wu Q, Xie Y, Lu F, Guo Q, Shen Z, Jin X, Yan N
To Be Published