EMD-71975

Single-particle
2.5 Å
EMD-71975
3D View Gallery
Deposition: 06/08/2025
Map released: 20/05/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-71975

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9pxn summary report (pdf.gz) Map-9pxn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human apo HCN1 nanodisc

EMD-71975

Single-particle
2.5 Å
EMD-71975
3D View Gallery
Deposition: 06/08/2025
Map released: 20/05/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Homotetrameric HCN1 complex (fusion with Thermostable Green Protein)
Fitted models: 9pxn

Deposition Authors: Chinn A, Chanda B
Lipid bilayers determine allostery but not intrinsic affinity of cAMP to pacemaker channels.
Idikuda V, Roy Chowdhury S, Chinn A, Chang Y, Rahman S, Ren Q, Bao H, Fu Z, Goldsmith RH, Chanda B
(2026) Nat Commun , 17
PUBMED: 42069694
DOI: doi:10.1038/s41467-026-72591-6
ISSN: 2041-1723