About EMDB
Meet the team
The Electron Microscopy Data Bank (EMDB) team operates out of EMBL-EBI and you can read more about us here.
EMDB history
The EMDB is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography (for more information, see the EMDB Policies).
EMDB was founded at EMBL-EBI in 2002 under the leadership of Kim Henrick. From 2007, the archive has been operated jointly by EMBL-EBI and the Research Collaboratory for Structural Bioinformatics (RCSB)a. In 2013, the Protein Data Bank Japan (PDBj) also became involved in EMDB. As of the first of January, 2021, EMDB is an archive operated under the aegis of the Worldwide Protein Data Bank (wwPDB), and has also joined that organisation as a full member.
Results of cryo-EM studies are archived in three collaborating archives:
- EMDB stores the processed 3D volumes and tomograms;
- PDB stores any atomic models that have been constructed based on EMDB data;
- EMPIAR stores the raw EM data underpinning the data in EMDB/PDB.
Data for EMDB and PDB can be deposited through the wwPDB deposition and annotation system OneDep.
EMPIAR (Electron Microscopy Public Image Archive) is a companion archive to EMDB, founded at and operated by EMBL-EBI, and with a mirror site at PDBj.
Citing EMDB
Please cite the following publication in your papers and on websites: The wwPDB Consortium, EMDB—the Electron Microscopy Data Bank, Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D456–D465, https://doi.org/10.1093/nar/gkad1019
To cite individual entries, please quote the EMDB accession code(s) and cite the original publication(s) in which the entries are described.
EMDB logos and branding should not be used on public-facing websites unless explicit prior permission has been obtained from us. However, if you want to use an EMDB logo in a presentation or report, you can use the images in the following table royalty-free and without the need to obtain prior permission from us.
More information
Please see our FAQ, Policies, description of the EMDB data model, or contact the EMDB helpdesk.
Funding
The work on EMDB at EMBL-EBI has been funded in the past by the European Commission, NIH, UKRI-BBSRC and EMBL-EBI (through the EMBL member states). It is currently funded by the Wellcome Trust and EMBL-EBI.
Quick links
Recent Entries
(Show all)Cryo-EM structure of KCa3.1_II/calmodulin channel in complex with SKA111.
Cryo-EM structure of KCa2.2/calmodulin channel in complex with SKA31.
Localized reconstruction of packaging hexamer P4 from polar region of transcribing double-layered particle of bacteriophage phi6
Transcribing double-layered particle of bacteriophage phi6 reconstructed with icosahedral symmetry
Localized reconstruction of packaging hexamer P4 from equatorial region of transcribing single-layered particle of bacteriophage phi6
Structure of CliM-stalled Bacillus subtilis 70S ribosome with empty A-site
Localized reconstruction of packaging hexamer P4 from polar region of transcribing single-layered particle of bacteriophage phi6
Structure of CliM-stalled Bacillus subtilis 70S ribosome with release factor bound in the A-site
Structure of CliM-stalled Bacillus subtilis 70S ribosome with tRNA-Tyr in the A-site
Cryo-EM structure of the adhesion GPCR ADGRV1 in complex with a nanobody
CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1
Transcribing single-layered particle of bacteriophage phi6 reconstructed with icosahedral symmetry
Localized reconstruction of polymerase P2 from transcribing single-layered particle of bacteriophage phi6 in stage C
Localized reconstruction of polymerase P2 from transcribing single-layered particle of bacteriophage phi6 in stage B
Localized reconstruction of polymerase P2 from transcribing double-layered particle of bacteriophage phi6 in stage A1
Localized reconstruction consensus map of minor protein P7 from transcribing particles of bacteriophage phi6
Localized reconstruction of polymerase P2 from transcribing double-layered particle of bacteriophage phi6 in stage A3
Localized reconstruction of packaging hexamer P4 from equatorial region of transcribing double-layered particle of bacteriophage phi6
Localized reconstruction of polymerase P2 from transcribing double-layered particle of bacteriophage phi6 in stage A2
Asymmetric reconstruction of transcribing double-layered particle of bacteriophage phi6, disassembly intermediate 1
Asymmetric reconstruction of transcribing double-layered particle of bacteriophage phi6, disassembly intermediate 2
Transcription-arrested single-layered particle of bacteriophage phi6 reconstructed with D3 symmetry
Transcription-arrested double-layered particle of bacteriophage phi6 reconstructed with icosahedral symmetry
Transcription-arrested single-layered particle of bacteriophage phi6 reconstructed with icosahedral symmetry
Localized reconstruction of asymmetric unit from transcribing double-layered particle of bacteriophage phi6
Asymmetric reconstruction of transcribing double-layered particle of bacteriophage phi6, disassembly intermediate 3
Asymmetric reconstruction of transcribing double-layered particle of bacteriophage phi6, disassembly intermediate 4
Transcription-arrested double-layered particle of bacteriophage phi6 reconstructed with D3 symmetry
Localized reconstruction of asymmetric unit from transcribing single-layered particle of bacteriophage phi6
Localized reconstruction of asymmetric unit from transcribing single-layered particle of bacteriophage phi6 in an over-expanded state
Structure of WT E.coli ribosome with complexed filament nascent chain at length 47, with P-site tRNA
a5b3 GABAAR bound to GABA and Mb25 in a desensitized state in saposin nanodiscs after short GABA treatment
Structure of WT E.coli ribosome with complexed filament nascent chain at length 31, with P-site tRNAs
Gephyrin E-domain dimer with additional density on top of the dimer interface
Gephyrin E-domain dimer with additional density on the side of the dimer interface
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Closed2 tetramer
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Open Tetramer
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Closed1 tetramer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Empty monomer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. cofactor-monomer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Cofactor/ligand-monomer
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. cofactor/ligand-monomer in Closed2 tetramer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Closed2 tetramer with cofactor/ligand-monomer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. Total-monomer
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. cofactor/ligand-monomer in Closed1 tetramer.
CryoEM map of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis obtained in the presence of NAD+ and L-glutamate. cofactor/ligand-monomer in Open tetramer.
Structure of Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase embedded in nanodisc
Structure of the Cytochrome o ubiquinol oxidase embedded in the nanodisc
Structure of the co-purified multidrug transporter subunit ACRB in nandisc
Icosahedral reconstruction of Semliki Forest virus in complex with ApoER2 LA5
Composite density map of Semliki Forest virus in complex with ApoER2 LA5
Semliki Forest virus trimer 1 in complex with ApoER2 ligand-binding domain
Icosahedral reconstruction of Semliki Forest virus in complex with ApoER2 ligand-binding domain
Semliki Forest virus trimer 2 in complex with ApoER2 ligand-binding domain
Composite density map of Semliki Forest virus in complex with ApoER2 ligand-binding domain
In situ structure of wild-type HIV-1 CA hexamer prior to nuclear import
In situ structure of wild-type HIV-1 CA hexamer post nuclear import
In situ structure of the H1-bound nucleosome in stacking nucleosomes
Cryo-EM structure of Z-DNA binding antibody Z-D11 in complex with left-handed Z-DNA
Cryo-EM structure of Z22 antibody in complex with left-handed Z-DNA (trimer)
Cryo-EM structure of Z22 mAb in complex with left-handed Z-DNA (dimer of trimer)
Hexamer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate
Cyro-EM structure of prefusion RSV fusion glycoprotein in complex with Ziresovir and motavizumab Fab
Cryo-EM structure of the glucose-specific PTS transporter IIC from V. cholerae in the inward-facing conformation
Ku70/80 with Ku70 linker and SAP domain bound to a 153 bp H2AX nucleosome
Constituent EM map: Focused refinement on TaF/TMD/CTD of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)
Constituent EM map: Focused refinement on TaF/TMD/CTD of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)
Raw consensus map of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)
Constituent EM map: Focused refinement on S2S3 of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)
Raw consensus map of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)
Raw consensus map of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)
Constituent EM map: Focused refinement on S2S3 of mouse RyR1 (Ca2+/CFF/ATP dataset; open pore)
Constituent EM map: Focused refinement on TaF/TMD/CTD of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)
Constituent EM map: Focused refinement on S2S3 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; open pore)
Raw consensus map of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)
Constituent EM map: Focused refinement on TaF/TMD/CTD of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)
Raw consensus map of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)
Constituent EM map: Focused refinement on TaF/TMD/CTD of mouse RyR1 (Ca2+/CFF/ATP dataset; closed pore)
Constituent EM map: Focused refinement on S2S3 of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)
Megrivirus E 3' internal ribosome entry site (IRES) RNA core region bound to rabbit ribosome
Constituent EM map: Focused refinement on S2S3 of mouse RyR1 with simvastatin (Ca2+/CFF/ATP dataset; closed pore)
Pseudomonas putida Pore-Forming Toxin Tke5 in complex with its cognate Type VI adaptor protein Tap3
Cryo-EM structure of sarkosyl insoluble amyloid-beta 42 filaments extracted from human brain tissue
Cryo-EM structure of the poly(4-styrenesulfonic acid-co-maleic acid) [PSCMA]-extractable amyloid-beta 42 oligomer from human brain tissue (Conformation 2)
Low resolution cryo-EM reconstruction of the DY2 collagen mimetic fibrils
Helical Reconstruction of the Complex of Pseudo-Acetylated Human Cardiac Actin (K326/328Q) and Tropomyosin
Helical Reconstruction of the Human Cardiac F-Actin-Tropomyosin Complex
CNGA1 channel intermediate state in nanodisc with brain PIP2 cGMP-bound
CNGA1 channel intermediate state in nanodisc with diC8-PIP2 cGMP-bound
Structure of disulfide-crosslinked S. cerevisiae Hrd1 dimer bound to one copy of Hrd3 in MSP1D1 nanodisc
Cryo-EM structure of F-ATP synthase from Mycobacteroides abscessus (Rotational State 3)
Cryo-EM structure of F-ATP synthase c-ring from Mycobacteroides abscessus (Backbone)
Cryo-EM structure of F-ATP synthase from Mycobacteroides abscessus (Rotational State 1)
Cryo-EM structure of F-ATP synthase from Mycobacteroides abscessus (Rotational State 2)
Cryo-EM map of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) jetted control sample
Cryo-EM structure of KCa3.1_I/calmodulin channel in complex with SKA111.
Identification and non-clinical characterization of SAR444200, a novel anti-GPC3 T-cell engager for the treatment of GPC3+ solid tumors
Cryo-EM structure of KCa3.1_II/calmodulin channel in complex with SKA31.
Cryo-EM structure of KCa3.1_I/calmodulin channel in complex with SKA31.
Structural Basis of Pausing During Transcription Initiation in Mycobacterium tuberculosis
Structural Basis of Pausing During Transcription Initiation in Mycobacterium tuberculosis
Structural Basis of Pausing During Transcription Initiation in Mycobacterium tuberculosis
The 1:1 cryo-EM structure of BAP1/ASXL1-K351Ub in complex with H2AK119Ub nucleosome
SPA of purified HIV-1 CA protein in vitro assembled with IP6 (mature morphology). 50 uM LEN was added post assembly.
Cryo-EM structure of human 80S ribosome in complex with montanine
cryo-EM density map of SFTSV virus complexed with with hA5-6 (W30B/W53) Fab
CryoEM structure of the tetrahedral M42 aminopeptidase from M. jannaschii
Cryo-EM structure of hIAPP fibrils extracted from a donor with T2D and pancreatic cancer
reconstructed map of the 3-fold axis region of SFTSV virus complexed with hA5-6 (W30B/W53) Fab
Cryo-EM map of hIAPP fibrils extracted from a donor with T2D and pancreatic cancer
Cryo-EM map of hIAPP fibrils extracted from a donor with T2D and Intraductal Papillary Mucinous Neoplasm
The structure of the FIPV-1146 S trimer with mixed D0 conformations




