EMD-49551

Single-particle
2.91 Å
EMD-49551
3D View Gallery
Deposition: 04/03/2025
Map released: 14/01/2026
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49551

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Raw consensus map of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

EMD-49551

Single-particle
2.91 Å
EMD-49551
3D View Gallery
Deposition: 04/03/2025
Map released: 14/01/2026
Last modified: 14/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Complex of RyR1 with Calstabin-1 (EGTA condition)

Deposition Authors: Weninger G, Marks AR
Structural basis for simvastatin-induced skeletal muscle weakness associated with type 1 ryanodine receptor T4709M mutation.
Weninger G, Dridi H, Reiken S, Yuan Q, Zhao N, Groom L, Leigh J, Liu Y, Tchagou C, Kang J, Chang A, Luna-Figueroa E, Miotto MC, Wronska A, Dirksen RT, Marks AR
(2025) J Clin Inv , 135
PUBMED: 41392983
DOI: doi:10.1172/JCI194490
ISSN: 0021-9738
ASTM: JCINAO