EMD-48430

Single-particle
3.5 Å
EMD-48430
3D View Gallery
Deposition: 22/12/2024
Map released: 14/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48430

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9mnm summary report (pdf.gz) Map-9mnm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SPA of purified HIV-1 CA protein in vitro assembled with IP6 (mature morphology). 500 uM LEN was added post assembly.

EMD-48430

Single-particle
3.5 Å
EMD-48430
3D View Gallery
Deposition: 22/12/2024
Map released: 14/01/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: HIV-1, Human immunodeficiency virus type 1 BH10
Sample: HIV-1
Fitted models: 9mnm

Deposition Authors: Ricana CL , Dick RA
Lenacapavir prevents production of infectious HIV-1 by abrogating immature virus assembly.
Ricana CL , Brancato SG , Highland CM , Ekbataniamiri F , Ambrus K , Rey JS , Faerch M , Torbett BE , Perilla JR , Dick RA
(2026) bioRxiv
PUBMED: 41867786
DOI: doi:10.64898/2026.03.02.709178
ISSN: 2692-8205