EMD-72178
Cereblon Ternary Complex with Blimp1 and compound 5
EMD-72178
Single-particle3.2 Å
Deposition: 15/08/2025Map released: 14/01/2026
Last modified: 14/01/2026
Sample Organism:
Homo sapiens
Sample: Cereblon Ternary Complex with Blimp1 and compound 5
Fitted models: 9q33
Deposition Authors: Watson ER
,
Lander GC
Sample: Cereblon Ternary Complex with Blimp1 and compound 5
Fitted models: 9q33
Deposition Authors: Watson ER
,
Lander GC
Discovery and Characterization of Novel BLIMP-1 Heterobifunctional Ligand-Directed Degraders.
Simmons BJ ,
Groocock L ,
Moreno J ,
Peters DS,
Hughes ME,
Veeravalli V,
Crawford JM,
Chalkley M,
Griffith M,
Plooster M,
Hu B,
Gamez J,
Leisten J,
Barnes MJ ,
Chinn J,
Deb G,
Modi H,
Katepalli M,
Weiss D,
Won W,
Sun Z ,
Yu S,
Reid C,
Donnell AF ,
Li L,
Watson ER ,
Perrin-Ninkovic S,
Shi L ,
Narla RK,
Zapf CW,
Bence N,
Lopez-Girona A,
Riggs JR
(2025) J Med Chem , 68 , 25385 - 25402
,
Groocock L ,
Moreno J ,
Peters DS,
Hughes ME,
Veeravalli V,
Crawford JM,
Chalkley M,
Griffith M,
Plooster M,
Hu B,
Gamez J,
Leisten J,
Barnes MJ ,
Chinn J,
Deb G,
Modi H,
Katepalli M,
Weiss D,
Won W,
Sun Z ,
Yu S,
Reid C,
Donnell AF ,
Li L,
Watson ER ,
Perrin-Ninkovic S,
Shi L ,
Narla RK,
Zapf CW,
Bence N,
Lopez-Girona A,
Riggs JR
(2025) J Med Chem , 68 , 25385 - 25402
Grant Support:
- Other private: (United States)