Structure for peptidase homologue S09.980: cholinesterase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Drosophila melanogaster
mature peptidase	2.70 Å	1DX4	1DX4	1DX4	1DX4	1DX4	1DX4	Harel et al., 2000
mature peptidase	2.70 Å	1QO9	1QO9	1QO9	1QO9	1QO9	1QO9	Harel et al., 2000
mature peptidase	2.72 Å	1QON	1QON	1QON	1QON	1QON	1QON	Harel et al., 2000
Homo sapiens
mature peptidase	0.00 Å	1EHO	1EHO	1EHO	1EHO	1EHO	1EHO
mature peptidase	0.00 Å	1EHQ	1EHQ	1EHQ	1EHQ	1EHQ	1EHQ
mature peptidase	0.00 Å	1KCJ	1KCJ	1KCJ	1KCJ	1KCJ	1KCJ
mature peptidase	2.00 Å	1P0I	1P0I	1P0I	1P0I	1P0I	1P0I	Nicolet et al., 2003
mature peptidase	2.38 Å	1P0M	1P0M	1P0M	1P0M	1P0M	1P0M	Nicolet et al., 2003
mature peptidase	2.30 Å	1P0P	1P0P	1P0P	1P0P	1P0P	1P0P	Nicolet et al., 2003
mature peptidase	2.43 Å	1P0Q	1P0Q	1P0Q	1P0Q	1P0Q	1P0Q	Nicolet et al., 2003
mature peptidase	2.20 Å	1XLU	1XLU	1XLU	1XLU	1XLU	1XLU	Nachon et al., 2005
mature peptidase	2.25 Å	1XLV	1XLV	1XLV	1XLV	1XLV	1XLV	Nachon et al., 2005
mature peptidase	2.10 Å	1XLW	1XLW	1XLW	1XLW	1XLW	1XLW	Nachon et al., 2005
mature peptidase	2.75 Å	2J4C	2J4C	2J4C	2J4C	2J4C	2J4C	Frasco et al., 2007
mature peptidase	2.80 Å	2PM8	2PM8	2PM8	2PM8	2PM8	2PM8	Ngamelue et al., 2007
mature peptidase	2.30 Å	2WID	2WID	2WID	2WID	2WID	2WID	Carletti et al., 2009
mature peptidase	2.25 Å	2WIF	2WIF	2WIF	2WIF	2WIF	2WIF	Carletti et al., 2009
mature peptidase	2.15 Å	2WIG	2WIG	2WIG	2WIG	2WIG	2WIG	Carletti et al., 2009
mature peptidase	2.10 Å	2WIJ	2WIJ	2WIJ	2WIJ	2WIJ	2WIJ	Carletti et al., 2009
mature peptidase	2.10 Å	2WIK	2WIK	2WIK	2WIK	2WIK	2WIK	Carletti et al., 2009
mature peptidase	3.10 Å	2WIL	2WIL	2WIL	2WIL	2WIL	2WIL	Carletti et al., 2009
mature peptidase	2.00 Å	2WSL	2WSL	2WSL	2WSL	2WSL	2WSL	Carletti et al., 2009
mature peptidase	2.10 Å	2XMB	2XMB	2XMB	2XMB	2XMB	2XMB	Nachon et al., 2011
mature peptidase	2.40 Å	2XMC	2XMC	2XMC	2XMC	2XMC	2XMC	Nachon et al., 2011
mature peptidase	2.30 Å	2XMD	2XMD	2XMD	2XMD	2XMD	2XMD	Nachon et al., 2011
mature peptidase	2.70 Å	2XMG	2XMG	2XMG	2XMG	2XMG	2XMG	Nachon et al., 2011
mature peptidase	2.10 Å	2XQF	2XQF	2XQF	2XQF	2XQF	2XQF	Wandhammer et al., 2011
mature peptidase	2.30 Å	2XQG	2XQG	2XQG	2XQG	2XQG	2XQG	Wandhammer et al., 2011
mature peptidase	2.60 Å	2XQI	2XQI	2XQI	2XQI	2XQI	2XQI	Wandhammer et al., 2011
mature peptidase	2.40 Å	2XQJ	2XQJ	2XQJ	2XQJ	2XQJ	2XQJ	Wandhammer et al., 2011
mature peptidase	2.40 Å	2XQK	2XQK	2XQK	2XQK	2XQK	2XQK	Wandhammer et al., 2011
mature peptidase	2.50 Å	2Y1K	2Y1K	2Y1K	2Y1K	2Y1K	2Y1K	Carletti et al., 2011
mature peptidase	2.10 Å	3DJY	3DJY	3DJY	3DJY	3DJY	3DJY	Carletti et al., 2008
mature peptidase	2.31 Å	3DKK	3DKK	3DKK	3DKK	3DKK	3DKK	Carletti et al., 2008
mature peptidase	2.98 Å	3O9M	3O9M	3O9M	3O9M	3O9M	3O9M	Asojo et al., 2011
mature peptidase	2.50 Å	4AQD	4AQD	4AQD	4AQD	4AQD	4AQD	Brazzolotto et al., 2012
mature peptidase	2.40 Å	4AXB	4AXB	4AXB	4AXB	4AXB	4AXB	Wandhammer et al., 2013
mature peptidase	2.35 Å	4B0O	4B0O	4B0O	4B0O	4B0O	4B0O	Wandhammer et al., 2013
mature peptidase	2.50 Å	4B0P	4B0P	4B0P	4B0P	4B0P	4B0P	Wandhammer et al., 2013
mature peptidase	2.70 Å	4BBZ	4BBZ	4BBZ	4BBZ	4BBZ	4BBZ	Carletti et al., 2013
mature peptidase	2.10 Å	4BDS	4BDS	4BDS	4BDS	4BDS	4BDS	Nachon et al., 2013
mature peptidase	2.70 Å	4TPK	4TPK	4TPK	4TPK	4TPK	4TPK	Brus et al., 2014
mature peptidase	2.70 Å	4XII	4XII	4XII	4XII	4XII	4XII	Knez et al., 2015
complex with n- ((1-benzylpiperidin-3-yl)methyl)-n-methylnaphthalene-2-sulfonamide *caveat 5dyt nag a 606 has wrong chirality at atom c1 nag a 607 has wrong *caveat 2 5dyt chirality at atom c1 nag a	2.55 Å	5DYT	5DYT	5DYT	5DYT	5DYT	5DYT
complex with n- ((1-benzylpiperidin-3-yl)methyl)-n-(2-methoxyethyl)naphthalene-2- sulfonamide *caveat 5dyw 5hf a 601 has wrong chirality at atom c07 nag a 621 has *caveat 2 5dyw wrong chirality at at	2.50 Å	5DYW	5DYW	5DYW	5DYW	5DYW	5DYW
complex with n- ((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide *caveat 5dyy nag a 611 has wrong chirality at atom c1 nag a 612 has wrong *caveat 2 5dyy chirality at atom c1 ful a 613 has w	2.65 Å	5DYY	5DYY	5DYY	5DYY	5DYY	5DYY
discovery and structure-activity relationships of a highly selective butyrylcholinesterase inhibitor by structure-based virtual screening	2.80 Å	5K5E	5K5E	5K5E	5K5E	5K5E	5K5E
complex with N-propargyliperidines	2.52 Å	5LKR	5LKR	5LKR	5LKR	5LKR	5LKR
crystal structure of hubche with n-((1-(2,3-dihydro-1h-inden-2-yl) piperidin-3-yl)methyl)-n-(2-(dimethylamino)ethyl)-2-naphthamide. *caveat 5nn0 fuc a 605 has wrong chirality at atom c1 nag a 608 has wrong *caveat 2 5nn0 chirality at atom c1	2.10 Å	5NN0	5NN0	5NN0	5NN0	5NN0	5NN0
crystal structure of a variant of human butyrylcholinesterase expressed in bacteria.	2.48 Å	6EMI	6EMI	6EMI	6EMI	6EMI	6EMI
complex with decamethonium	2.30 Å	6EP4	6EP4	6EP4	6EP4	6EP4	6EP4
complex with ethopropazine	2.35 Å	6EQP	6EQP	6EQP	6EQP	6EQP	6EQP
complex with huprine 19	2.40 Å	6EQQ	6EQQ	6EQQ	6EQQ	6EQQ	6EQQ
complex with propidium	2.98 Å	6ESJ	6ESJ	6ESJ	6ESJ	6ESJ	6ESJ
complex with thioflavine t	2.80 Å	6ESY	6ESY	6ESY	6ESY	6ESY	6ESY
butyrylcolinesterase expressed in cho cells co-crystallised with a rivastigmine analogue	2.60 Å	6EUL	6EUL	6EUL	6EUL	6EUL	6EUL
butyrylcolinesterase expressed in cho cells co-crystallised with a rivastigmine analogue	2.60 Å	6EYF	6EYF	6EYF	6EYF	6EYF	6EYF
human butyrylcholinesterase carbamylated.	2.70 Å	6EZ2	6EZ2	6EZ2	6EZ2	6EZ2	6EZ2
complex with n-propargyliperidines	2.60 Å	6F7Q	6F7Q	6F7Q	6F7Q	6F7Q	6F7Q
complex with the s enantiomer of a chlorotacrine-tryptophan multi-target inhibitor.	2.38 Å	6I0B	6I0B	6I0B	6I0B	6I0B	6I0B
complex with the r enantiomer of a chlorotacrine-tryptophan multi-target inhibitor.	2.68 Å	6I0C	6I0C	6I0C	6I0C	6I0C	6I0C
cryoem reconstruction of full-length, fully-glycosylated human butyrylcholinesterase tetramer	5.70 Å	6I2T	6I2T	6I2T	6I2T	6I2T	6I2T
complex with (s)-2-(butylamino)-n-(2- cycloheptylethyl)-3-(1h-indol-3-yl)propanamide	1.90 Å	6QAA	6QAA	6QAA	6QAA	6QAA	6QAA
complex with (s)-n-(1-((2- cycloheptylethyl)amino)-3-(1h-indol-3-yl)-1-oxopropan-2-yl)-n,n- dimethylbutan-1-aminium	2.49 Å	6QAB	6QAB	6QAB	6QAB	6QAB	6QAB
complex with (s)-2-(butylamino)-n-(3- cycloheptylpropyl)-3-(1h-indol-3-yl)propanamide	2.77 Å	6QAC	6QAC	6QAC	6QAC	6QAC	6QAC
complex with ((s)-2-(butylamino)-n-(2- (4-(dimethylamino)cyclohexyl)ethyl)-3-(1h-indol-3-yl)propanamide	2.50 Å	6QAD	6QAD	6QAD	6QAD	6QAD	6QAD
complex with (s)-n2-butyl-n1-(2- cycloheptylethyl)-3-(1h-indol-3-yl)-n1,n2-dimethylpropane-1,2-diamine	2.49 Å	6QAE	6QAE	6QAE	6QAE	6QAE	6QAE
Torpedo californica
mature peptidase	2.80 Å	1ACJ	1ACJ	1ACJ	1ACJ	1ACJ	1ACJ	Harel et al., 1993
mature peptidase	2.80 Å	1ACL	1ACL	1ACL	1ACL	1ACL	1ACL	Harel et al., 1993
mature peptidase	2.80 Å	1AMN	1AMN	1AMN	1AMN	1AMN	1AMN
mature peptidase	2.80 Å	1AX9	1AX9	1AX9	1AX9	1AX9	1AX9	Ravelli et al., 1998
mature peptidase	2.60 Å	1CFJ	1CFJ	1CFJ	1CFJ	1CFJ	1CFJ	Millard et al., 1999
mature peptidase	2.30 Å	1DX6	1DX6	1DX6	1DX6	1DX6	1DX6	Greenblatt et al., 1999
mature peptidase	2.85 Å	1E3Q	1E3Q	1E3Q	1E3Q	1E3Q	1E3Q	Felder et al., 2002
mature peptidase	2.10 Å	1E66	1E66	1E66	1E66	1E66	1E66	Dvir et al., 2002
mature peptidase	1.80 Å	1EA5	1EA5	1EA5	1EA5	1EA5	1EA5	Dvir et al., 2002
mature peptidase	4.50 Å	1EEA	1EEA	1EEA	1EEA	1EEA	1EEA
mature peptidase	2.50 Å	1EVE	1EVE	1EVE	1EVE	1EVE	1EVE	Kryger et al., 1999
mature peptidase	3.00 Å	1FSS	1FSS	1FSS	1FSS	1FSS	1FSS	Harel et al., 1995
mature peptidase	2.10 Å	1GPK	1GPK	1GPK	1GPK	1GPK	1GPK	Dvir et al., 2002
mature peptidase	2.35 Å	1GPN	1GPN	1GPN	1GPN	1GPN	1GPN	Dvir et al., 2002
mature peptidase	2.20 Å	1GQR	1GQR	1GQR	1GQR	1GQR	1GQR	Bar-On et al., 2002
mature peptidase	3.00 Å	1GQS	1GQS	1GQS	1GQS	1GQS	1GQS	Bar-On et al., 2002
mature peptidase	2.15 Å	1H22	1H22	1H22	1H22	1H22	1H22	Wong et al., 2003
mature peptidase	2.15 Å	1H23	1H23	1H23	1H23	1H23	1H23	Wong et al., 2003
mature peptidase	2.50 Å	1HBJ	1HBJ	1HBJ	1HBJ	1HBJ	1HBJ	Doucet-Personeni et al., 2001
mature peptidase	0.00 Å	1JGA	1JGA	1JGA	1JGA	1JGA	1JGA
mature peptidase	0.00 Å	1JGB	1JGB	1JGB	1JGB	1JGB	1JGB
mature peptidase	2.30 Å	1JJB	1JJB	1JJB	1JJB	1JJB	1JJB	Koellner et al., 2002
mature peptidase	2.70 Å	1OCE	1OCE	1OCE	1OCE	1OCE	1OCE	Bartolucci et al., 1999
mature peptidase	2.20 Å	1ODC	1ODC	1ODC	1ODC	1ODC	1ODC	Rydberg et al., 2006
mature peptidase	2.05 Å	1QID	1QID	1QID	1QID	1QID	1QID	Weik et al., 2000
mature peptidase	2.10 Å	1QIE	1QIE	1QIE	1QIE	1QIE	1QIE	Weik et al., 2000
mature peptidase	2.10 Å	1QIF	1QIF	1QIF	1QIF	1QIF	1QIF	Weik et al., 2000
mature peptidase	2.30 Å	1QIG	1QIG	1QIG	1QIG	1QIG	1QIG	Weik et al., 2000
mature peptidase	2.50 Å	1QIH	1QIH	1QIH	1QIH	1QIH	1QIH	Weik et al., 2000
mature peptidase	2.65 Å	1QII	1QII	1QII	1QII	1QII	1QII	Weik et al., 2000
mature peptidase	2.80 Å	1QIJ	1QIJ	1QIJ	1QIJ	1QIJ	1QIJ	Weik et al., 2000
mature peptidase	2.90 Å	1QIK	1QIK	1QIK	1QIK	1QIK	1QIK	Weik et al., 2000
mature peptidase	3.00 Å	1QIM	1QIM	1QIM	1QIM	1QIM	1QIM	Weik et al., 2000
mature peptidase	2.50 Å	1QTI	1QTI	1QTI	1QTI	1QTI	1QTI	Bartolucci et al., 2001
mature peptidase	2.20 Å	1SOM	1SOM	1SOM	1SOM	1SOM	1SOM	Millard et al., 1999
mature peptidase	2.61 Å	1U65	1U65	1U65	1U65	1U65	1U65	Harel et al., 2005
mature peptidase	2.40 Å	1UT6	1UT6	1UT6	1UT6	1UT6	1UT6	Rydberg et al., 2006
mature peptidase	2.50 Å	1VOT	1VOT	1VOT	1VOT	1VOT	1VOT	Raves et al., 1997
mature peptidase	2.40 Å	1VXO	1VXO	1VXO	1VXO	1VXO	1VXO
mature peptidase	2.20 Å	1VXR	1VXR	1VXR	1VXR	1VXR	1VXR
mature peptidase	2.16 Å	1W4L	1W4L	1W4L	1W4L	1W4L	1W4L	Greenblatt et al., 2004
mature peptidase	2.05 Å	1W6R	1W6R	1W6R	1W6R	1W6R	1W6R	Greenblatt et al., 2004
mature peptidase	2.40 Å	1W75	1W75	1W75	1W75	1W75	1W75	Greenblatt et al., 2004
mature peptidase	2.30 Å	1W76	1W76	1W76	1W76	1W76	1W76	Greenblatt et al., 2004
mature peptidase	2.30 Å	1ZGB	1ZGB	1ZGB	1ZGB	1ZGB	1ZGB	Haviv et al., 2005
mature peptidase	2.10 Å	1ZGC	1ZGC	1ZGC	1ZGC	1ZGC	1ZGC	Haviv et al., 2005
mature peptidase	2.50 Å	2ACE	2ACE	2ACE	2ACE	2ACE	2ACE	Raves et al., 1997
mature peptidase	2.40 Å	2ACK	2ACK	2ACK	2ACK	2ACK	2ACK	Ravelli et al., 1998
mature peptidase	2.40 Å	2BAG	2BAG	2BAG	2BAG	2BAG	2BAG	Bartolucci et al., 2006
mature peptidase	2.15 Å	2C4H	2C4H	2C4H	2C4H	2C4H	2C4H	Colletier et al., 2006
mature peptidase	2.30 Å	2C58	2C58	2C58	2C58	2C58	2C58	Colletier et al., 2006
mature peptidase	2.60 Å	2C5F	2C5F	2C5F	2C5F	2C5F	2C5F	Colletier et al., 2006
mature peptidase	1.95 Å	2C5G	2C5G	2C5G	2C5G	2C5G	2C5G	Colletier et al., 2006
mature peptidase	2.20 Å	2CEK	2CEK	2CEK	2CEK	2CEK	2CEK	Colletier et al., 2006
mature peptidase	2.15 Å	2CKM	2CKM	2CKM	2CKM	2CKM	2CKM	Rydberg et al., 2006
mature peptidase	2.50 Å	2CMF	2CMF	2CMF	2CMF	2CMF	2CMF	Rydberg et al., 2006
mature peptidase	2.30 Å	2DFP	2DFP	2DFP	2DFP	2DFP	2DFP	Millard et al., 1999
mature peptidase	2.60 Å	2J3D	2J3D	2J3D	2J3D	2J3D	2J3D
mature peptidase	2.80 Å	2J3Q	2J3Q	2J3Q	2J3Q	2J3Q	2J3Q	Harel et al., 2008
mature peptidase	2.80 Å	2J4F	2J4F	2J4F	2J4F	2J4F	2J4F	Kreimer et al., 1994
mature peptidase	2.40 Å	2V96	2V96	2V96	2V96	2V96	2V96	Colletier et al., 2007
mature peptidase	2.40 Å	2V97	2V97	2V97	2V97	2V97	2V97	Colletier et al., 2007
mature peptidase	3.00 Å	2V98	2V98	2V98	2V98	2V98	2V98	Colletier et al., 2007
mature peptidase	2.40 Å	2VA9	2VA9	2VA9	2VA9	2VA9	2VA9	Colletier et al., 2007
mature peptidase	2.30 Å	2VJA	2VJA	2VJA	2VJA	2VJA	2VJA	Colletier et al., 2008
mature peptidase	2.39 Å	2VJB	2VJB	2VJB	2VJB	2VJB	2VJB	Colletier et al., 2008
mature peptidase	2.20 Å	2VJC	2VJC	2VJC	2VJC	2VJC	2VJC	Colletier et al., 2008
mature peptidase	2.30 Å	2VJD	2VJD	2VJD	2VJD	2VJD	2VJD	Colletier et al., 2008
mature peptidase	2.71 Å	2VQ6	2VQ6	2VQ6	2VQ6	2VQ6	2VQ6
mature peptidase	2.40 Å	2VT6	2VT6	2VT6	2VT6	2VT6	2VT6	Colletier et al., 2008
mature peptidase	2.20 Å	2VT7	2VT7	2VT7	2VT7	2VT7	2VT7	Colletier et al., 2008
mature peptidase	2.69 Å	2W6C	2W6C	2W6C	2W6C	2W6C	2W6C	Paz et al., 2009
mature peptidase	2.43 Å	2W9I	2W9I	2W9I	2W9I	2W9I	2W9I	Paz et al., 2012
mature peptidase	1.95 Å	2WFZ	2WFZ	2WFZ	2WFZ	2WFZ	2WFZ	Sanson et al., 2009
mature peptidase	2.20 Å	2WG0	2WG0	2WG0	2WG0	2WG0	2WG0	Sanson et al., 2009
mature peptidase	2.20 Å	2WG1	2WG1	2WG1	2WG1	2WG1	2WG1	Sanson et al., 2009
mature peptidase	1.95 Å	2WG2	2WG2	2WG2	2WG2	2WG2	2WG2	Sanson et al., 2009
mature peptidase	2.30 Å	2XI4	2XI4	2XI4	2XI4	2XI4	2XI4	Sanson et al., 2011
mature peptidase	0.00 Å	3ACE	3ACE	3ACE	3ACE	3ACE	3ACE
mature peptidase	2.39 Å	3GEL	3GEL	3GEL	3GEL	3GEL	3GEL
mature peptidase	2.26 Å	3I6M	3I6M	3I6M	3I6M	3I6M	3I6M	Bartolucci et al., 2010
mature peptidase	2.19 Å	3I6Z	3I6Z	3I6Z	3I6Z	3I6Z	3I6Z	Bartolucci et al., 2010
mature peptidase	2.34 Å	3M3D	3M3D	3M3D	3M3D	3M3D	3M3D
mature peptidase	2.26 Å	3ZV7	3ZV7	3ZV7	3ZV7	3ZV7	3ZV7	Bartolucci et al., 2012
mature peptidase	0.00 Å	4ACE	4ACE	4ACE	4ACE	4ACE	4ACE
mature peptidase	2.30 Å	4TVK	4TVK	4TVK	4TVK	4TVK	4TVK	Nepovimova et al., 2014
mature peptidase	2.80 Å	4W63	4W63	4W63	4W63	4W63	4W63
mature peptidase	2.60 Å	4X3C	4X3C	4X3C	4X3C	4X3C	4X3C
mature peptidase	2.57 Å	5BWB	5BWB	5BWB	5BWB	5BWB	5BWB	Legler et al., 2015
mature peptidase	2.45 Å	5BWC	5BWC	5BWC	5BWC	5BWC	5BWC	Legler et al., 2015
acetylcholinesterase methylene blue no peg	2.70 Å	5DLP	5DLP	5DLP	5DLP	5DLP	5DLP
mature peptidase	2.65 Å	5E2I	5E2I	5E2I	5E2I	5E2I	5E2I
acetylcholinesterase methylene blue no peg	2.54 Å	5E4J	5E4J	5E4J	5E4J	5E4J	5E4J
acetylcholinesterase methylene blue with peg	2.43 Å	5E4T	5E4T	5E4T	5E4T	5E4T	5E4T
crystal structure of msf-aged torpedo californica acetylcholinesterase	2.10 Å	5EHX	5EHX	5EHX	5EHX	5EHX	5EHX
complex with alkylene-linked bis-tacrine dimer (7 carbon linker)	2.10 Å	5EI5	5EI5	5EI5	5EI5	5EI5	5EI5
complex with the n- methyl-indoxylacetate hydrolysis products	2.40 Å	5IH7	5IH7	5IH7	5IH7	5IH7	5IH7
torpedo californica acetylcholinesterase in complex with a non-chiral donepezil-like inhibitor 17	2.17 Å	5NAP	5NAP	5NAP	5NAP	5NAP	5NAP
torpedo californica acetylcholinesterase in complex with a non-chiral donepezil-like compound 20	2.25 Å	5NAU	5NAU	5NAU	5NAU	5NAU	5NAU
torpedo californica acetylcholinesterase in complex with a chlorotacrine-tryptophan hybrid inhibitor	2.50 Å	5NUU	5NUU	5NUU	5NUU	5NUU	5NUU
rivastigmine analogue bound to tc ache.	2.00 Å	6EUE	6EUE	6EUE	6EUE	6EUE	6EUE
t. californica ache in complex with a 3-hydroxy-2-pyridine aldoxime.	2.22 Å	6EWK	6EWK	6EWK	6EWK	6EWK	6EWK
torpedo californica ache in complex with indolic multi-target directedligand	2.20 Å	6EZG	6EZG	6EZG	6EZG	6EZG	6EZG
torpedo californica ache in complex with indolic multi-target directedligand ***caveat 6ezh nag a 601 has wrong chirality at atom c1	2.60 Å	6EZH	6EZH	6EZH	6EZH	6EZH	6EZH
carbamylated t. californica acetylcholineterase bound to uncharged hybrid reactivator 1	2.40 Å	6FLD	6FLD	6FLD	6FLD	6FLD	6FLD
carbamylated t. californica acetylcholineterase bound to uncharged hybrid reactivator 2	2.30 Å	6FQN	6FQN	6FQN	6FQN	6FQN	6FQN
non-aged form of torpedo californica acetylcholinesterase inhibited bynerve agent tabun	2.20 Å	6G17	6G17	6G17	6G17	6G17	6G17
complex with 9-amino-6-chloro-1,2,3,4-tetrahydro-10-methylacridin-10-ium	1.79 Å	6G1U	6G1U	6G1U	6G1U	6G1U	6G1U
complex with 12-amino-3-chloro-6,7,10,11-tetrahydro-5,9-dimethyl-7, 11-methanocycloocta[b]quinolin-5-ium	1.82 Å	6G1V	6G1V	6G1V	6G1V	6G1V	6G1V
complex with 2-1-[2-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino) ethyl]-1h-1,2,3-triazol-4-yl-n-[4-(hydroxy)-3- methoxybenzyl]acetamide	1.90 Å	6G1W	6G1W	6G1W	6G1W	6G1W	6G1W
torpedo californica acetylcholinesterase bound to uncharged hybrid reactivator 1	2.63 Å	6G4M	6G4M	6G4M	6G4M	6G4M	6G4M
torpedo californica acetylcholinesterase bound to uncharged hybrid reactivator 2	2.90 Å	6G4N	6G4N	6G4N	6G4N	6G4N	6G4N
non-aged form of torpedo californica acetylcholinesterase inhibited bytabun analog nedpa bound to uncharged reactivator 1	2.78 Å	6G4O	6G4O	6G4O	6G4O	6G4O	6G4O
non-aged form of torpedo californica acetylcholinesterase inhibited bytabun analog nedpa bound to uncharged reactivator 2	2.83 Å	6G4P	6G4P	6G4P	6G4P	6G4P	6G4P
complex to 1-(6-oxo-1,2,3,4,6,10b- hexahydropyrido[2,1-a]isoindol-10-yl)-3-(4-(((1-(2-((1,2,3,4- tetrahydroacridin-9-yl)amino)ethyl)-1h-1,2,3-triazol-4-yl)methoxy) methyl)pyridin-2-yl)urea ***caveat 6h12 fjk a 626 has wrong c	2.20 Å	6H12	6H12	6H12	6H12	6H12	6H12
complex to1-(4-((methyl((1-(2-((1,2,3,4-tetrahydroacridin-9-yl)amino)ethyl)-1h-1,2,3-triazol-4-yl)methyl) amino)methyl)pyridin-2-yl)-3-(6-oxo-1,2,3,4,6,10b-hexahydropyrido[2, 1-a]isoindol-10-yl)urea ***caveat 6h13 nag a 602 h	2.80 Å	6H13	6H13	6H13	6H13	6H13	6H13
complex to 1-(6-oxo-1,2,3,4,6,10b- hexahydropyrido[2,1-a]isoindol-10-yl)-3-(4-(1-(2-((1,2,3,4- tetrahydroacridin-9-yl)amino)ethyl)-1h-1,2,3-triazol-4-yl)pyridin-2- yl)urea	1.86 Å	6H14	6H14	6H14	6H14	6H14	6H14