PDBe 3dkk

X-ray diffraction
2.31Å resolution

Aged Form of Human Butyrylcholinesterase Inhibited by Tabun

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cholinesterase Chain: A
Molecule details ›
Chain: A
Length: 529 amino acids
Theoretical weight: 59.82 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06276 (Residues: 29-557; Coverage: 92%)
Gene names: BCHE, CHE1
Sequence domains:
Structure domains: Rossmann fold

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: I422
Unit cell:
a: 155.24Å b: 155.24Å c: 127.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.197 0.251
Expression system: Cricetulus griseus