PDBe 2xqg

X-ray diffraction
2.3Å resolution

X-ray Structure of human butyrylcholinesterase inhibited by racemic VR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cholinesterase Chain: A
Molecule details ›
Chain: A
Length: 527 amino acids
Theoretical weight: 59.47 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06276 (Residues: 31-557; Coverage: 92%)
Gene names: BCHE, CHE1
Structure domains: Rossmann fold

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: I422
Unit cell:
a: 154.6Å b: 154.6Å c: 127.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.162 0.215
Expression system: Cricetulus griseus