PDBe 6emi

X-ray diffraction
2.48Å resolution

Crystal structure of a variant of human butyrylcholinesterase expressed in bacteria.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cholinesterase Chains: A, B
Molecule details ›
Chains: A, B
Length: 532 amino acids
Theoretical weight: 60.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06276 (Residues: 29-557; Coverage: 92%)
Gene names: BCHE, CHE1
Sequence domains: Carboxylesterase family

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 159.84Å b: 75.17Å c: 122.07Å
α: 90° β: 93.37° γ: 90°
R-values:
R R work R free
0.224 0.222 0.255
Expression system: Escherichia coli